May 30, 2023

Focus Biomolecules at University of Pennsylvania

Focus Biomolecules will be exhibiting at the Spring 2023 Science, Technology & Career Event presented by the Penn Postdoc Association (PPA) of the University of Pennsylvania. […]
April 6, 2023

Orphan Receptor GPR139

Journal Club: Lisa Pallareti and coworkers at Univ. Copenhagen reported on the pharmacological characterization of agonists and antagonists of the orphan receptor GPR139. GPR139 is predominantly […]
March 30, 2023

Focus Biomolecules at AACR Cancer Research

Focus will be exhibiting at AACR, April 16-19 in Orlando, FL. Stop by our booth #3242 and chat with our scientists! Learn about our new cutting-edge […]
March 30, 2023

Product Focus: WP631

A small molecule that binds DNA at one bis-intercalation site can affect binding by another moiety nearby. WP631 is a novel bis-intercalating daunomycin dimer and potent […]
March 30, 2023

Chroman 1 for hPSC survival

New Product Focus: Chroman 1 is an important new small molecule tool for the generation and maintenance of stem cells. An extremely potent (1 pM) inhibitor […]
March 30, 2023

Surfactin analog effective in ARDS mouse model

Journal Club: Surfactin is a cyclic lipopeptide microbial metabolite produced by Bacillus subtilis that acts as a biosurfactant among other interesting activities. S.C. Yang and coworkers […]
March 30, 2023

Bempedoic acid effective for statin-intolerant patients

In The News: Bempedoic acid is an FDA-approved drug for the treatment of hypercholesterolemia sold under the brand name Nexletol. It is an ATP citrate lyase […]
March 23, 2023

Cyclopamine analog for cancer stem cells

Focus on Drug Discovery: Saridegib is a natural product-inspired drug candidate. Its prototype, cyclopamine was discovered as a teratogenic steroidal alkaloid that was found to cause […]
March 23, 2023

Leptomycin B rescues mitochondrial function

Journal Club: Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder caused by the expression of progerin, a Lamin A mutant. The study of HGPS […]