Natural products
‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).
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Fumagillin | MetAP-2 inhibitor
From $75.00CAS:23110-15-8Catalog Number:10-1146Activity:MetAP-2 inhibitorChemical Name:(2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid esterMolecular Weight:458.54Molecular Formula:C26H34>/sub>O7Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Orange solidPurity:95% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Fumonisin B1 | Blocks sphingolipid biosynthesis
From $120.00CAS:116355-83-0Catalog Number:10-2396Activity:Blocks sphingolipid biosynthesisMolecular Weight:721.85Molecular Formula:C34H59NO15Solubility:Soluble in Water (up to 25 mg/ml).Physical Properties:Beige solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Galanthamine HBr | Acetylcholinesterase inhibitor
From $40.00CAS:17991Catalog Number:10-1136Activity:Acetylcholinesterase inhibitorChemical Name:4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol, hydrobromideMolecular Weight:368.27Molecular Formula:C17H21NO3 HBrSolubility:Soluble in DMSO (up to 10 mg/ml) or in Water (up to 12 mg/ml).Physical Properties:Lyophillized solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Gambogic acid | Bcl-2 family/Survivin inhibitor
From $60.00CAS:2752-65-0Catalog Number:10-2188Activity:Bcl-2 family protein antagonist/Survivin inhibitorMolecular Weight:628.75Molecular Formula:C38H44O8Solubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 50 mg/ml)Physical Properties:Orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Garcinol | HAT inhibitor
From $70.00CAS:78824-30-3Catalog Number:10-1337Activity:HAT inhibitorMolecular Weight:602.8Molecular Formula:C38H50O6Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:Yellow solidPurity:>95%Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Garcinol is prone to oxidation. Protect from exposure to air.Shipping Code:RT -
Geldanamycin | HSP90 inhibitor
From $50.00CAS:30562-34-6Catalog Number:10-1084Activity:HSP90 inhibitorAlternate Names:NSC 122750; U-29135Chemical Name:9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione,9-carbamateMolecular Weight:560.65Molecular Formula:C29H40N2O9Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 monthsShipping Code:RT
