Natural products
‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).
-
Matrine | Induces RIP3-dependent necroptosis
From $30.00CAS:519-02-8Catalog Number:10-4612Activity:Induces RIP3-dependent necroptosisChemical Name:(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]napthyridin-10-oneSource:Isolated from Sophora flavescensMolecular Weight:248.36Molecular Formula:C15H24N2OSolubility:Soluble in Water (up to 25 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Meleagrin | Met inhibitor, anticancer activity
From $145.00CAS:71751-77-4Catalog Number:10-1599Activity:Met inhibitor, anticancer activityChemical Name:(3E,7aR,12aS-7a-(1,1-Dimethyl-2-propen-1-yl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-5-ylmethylene)-12-methoxy-1H,5H-imidazol[1’,2’:1,2]pyrido[2,3-b]indole-2,5(3H)-dioneMolecular Weight:433.46Molecular Formula:C23H23N5O4Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Tan solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Microcystin LR | Protein phosphatase PP1 and PP2A inhibitor
From $60.00CAS:101043-37-2Catalog Number:10-2719Activity:Protein phosphatase PP1 and PP2A inhibitorSource:Isolated from Microcystis aeruginosa, a fresh water cyanobacteriaMolecular Weight:995.17Molecular Formula:C49H74N10O12Solubility:Soluble in DMSO, methanol or ethanolPhysical Properties:Off-white lyophilized solidPurity:95% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, methanol or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Milbemectin | RDL GABA agonist and Glutamate-gated Cl channel activator
CAS:1799297-76-9Catalog Number:10-5257 -
Mithramycin A | Transcription inhibitor
From $42.00CAS:18378-89-7Catalog Number:10-2085Activity:Transcription inhibitorAlternate Names:A2371; Antibiotic LA 7017; Aureolic Acid; NSC 24559; PA 144; PlicamycinMolecular Weight:1085.15Molecular Formula:C52H76O24Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Monocrotaline | Induces pulmonary fibrosis
From $50.00CAS:315-22-0Catalog Number:10-2872Activity:Induces pulmonary fibrosisChemical Name:(3R,4R,5R)-4,5,8,10,12,13,13aR,13bR-Octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dioneAlternate Names:Crotaline; MCT; NSC28693Molecular Weight:325.36Molecular Formula:C16H23NO6Solubility:Soluble in DMSO (up to 50 mg/ml with warming), in Ethanol (up to 10 mg/ml with warming) or in organic solvents such as Chloroform (up to 50 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
