Highly Selective Inhibitors
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PLX5622 | Highly selective CSF1R inhibitor
From $70.00CAS:1303420-67-8Catalog Number:10-4726Activity:Highly selective CSF1R inhibitorChemical Names:6-Fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)methyl]pyridine-2-amineMolecular Weight:395.41Molecular Formula:C21H19F2N5OSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Pale yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Quizartinib | Selective FLT3 Inhibitor
From $50.00CAS:950769-58-1Catalog Number:10-4813Activity:Selective FLT3 inhibitorChemical Name:1-(5-(t-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)ureaAlternate Names:AC220Molecular Weight:560.67Molecular Formula:C29H32N6O4SSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
R428 | Potent and selective AXL inhibitor
From $75.00CAS:1037624-75-1Catalog Number:10-4676Activity:Potent and selective AXL inhibitorChemical Name:1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamineAlternate Names:Bemcentinib; BGB324Molecular Weight:506.64Molecular Formula:C30H34N8Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Roscovitine | p34/cdc2 inhibitor
From $45.00CAS:186692-46-6Catalog Number:10-1332Activity:p34/cdc2 inhibitorChemical Name:(R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-olMolecular Weight:354.46Molecular Formula:C19H26N6OSolubility:Soluble in DMSO (up to 10 mg/ml, with warming) or in Ethanol (up to 10 mg/ml).Physical Properties:White solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Ruxolitinib | JAK inhibitor
From $65.00CAS:941678-49-5Catalog Number:10-4511Activity:JAK inhibitorAlternate Names:INCB 018424Chemical Name:βR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrileMolecular Weight:306.37Molecular Formula:C17H18N6Solubility:Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT
