Other Kinases
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Matrine | Induces RIP3-dependent necroptosis
From $30.00CAS:519-02-8Catalog Number:10-4612Activity:Induces RIP3-dependent necroptosisChemical Name:(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]napthyridin-10-oneSource:Isolated from Sophora flavescensMolecular Weight:248.36Molecular Formula:C15H24N2OSolubility:Soluble in Water (up to 25 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Meleagrin | Met inhibitor, anticancer activity
From $145.00CAS:71751-77-4Catalog Number:10-1599Activity:Met inhibitor, anticancer activityChemical Name:(3E,7aR,12aS-7a-(1,1-Dimethyl-2-propen-1-yl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-5-ylmethylene)-12-methoxy-1H,5H-imidazol[1’,2’:1,2]pyrido[2,3-b]indole-2,5(3H)-dioneMolecular Weight:433.46Molecular Formula:C23H23N5O4Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Tan solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
ML167 | Clk4 inhibitor
From $75.00CAS:1285702-20-6Catalog Number:10-4543Activity:Clk4 inhibitorChemical Name:[5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanolMolecular Weight:335.36Molecular Formula:C19H17N2O3Solubility:Soluble in DMSO (greater than 25 mg/ml).Physical Properties:White solidPurity:>98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Necrostatin-1 | Inhibits necroptosis
From $55.00CAS:4311-88-0Catalog Number:10-1162Activity:Inhibits necroptosisChemical Name:5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-ImidazolidinoneMolecular Weight:259.33Molecular Formula:C13H13N3OSSolubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml).Physical Properties:Pale yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Necrosulfonamide | Necroptosis inhibitor / MLKL inhibitor
From $45.00CAS:1360614-48-7Catalog Number:10-4860Activity:Necroptosis inhibitor / MLKL inhibitorChemical Name:(2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamideMolecular Weight:461.47Molecular Formula:C18H15N5O6S2Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
