Antibacterials

Antibacterials (or antibiotics) are natural or synthetic compounds that kill (bactericidal) or block the growth (bacteriostatic) of bacteria. They target fundamental biochemical pathways that bacteria use for production of structural components such as cell wall as well as biosynthesis of macromolecules such as proteins and nucleic acids. Modulation of cell membrane permeability is another common target of many antibacterial agents.

  • Alamethicin | Pore-forming antimicrobial peptide

    CAS:
    27061-78-5
    Catalog Number:
    10-2055
    Activity:
    Pore-forming antimicrobial peptide
    Alternate Names:
    U-22324
    Molecular Weight:
    1964.31
    Molecular Formula:
    C92H150N22O25
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Methanol (up to 10 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC (mixture of alamethicin homologs)
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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  • Antibiotic A-23187 | Ca2+ ionophore

    CAS:
    52665-69-7
    Catalog Number:
    10-2284
    Activity:
    Ca2+ ionophore
    Alternate Names:
    Calcimycin
    Molecular Weight:
    523.62
    Molecular Formula:
    C29H37N3O6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
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  • Bedaquiline | Antituberculosis agent/bacterial ATP synthase inhibitor

    CAS:
    843663-66-1
    Catalog Number:
    10-4403
    Activity:
    Antituberculosis agent/Bacterial ATP synthase inhibitor
    Chemical Names:
    (1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-o
    Alternate Name:
    TMC207; R207910
    Molecular Weight:
    555.50
    Molecular Formula:
    C32H31BrN2O2
    Solubility:
    Soluble in DMSO (10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Bithionol | Glutamate dehydrogenase inhibitor

    CAS:
    97-18-7
    Catalog Number:
    10-4567
    Activity:
    Glutamate dehydrogenase inhibitor
    Chemical Name:
    Bis(2-hydroxy-3,5-dichlorophenyl)sulfide
    Molecular Weight:
    356.05
    Molecular Formula:
    C12H6Cl4O2S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
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  • Blasticidin S HCl | Antibiotic selection agent

    CAS:
    3513-03-9
    Catalog Number:
    10-2830
    Activity:
    Blasticidin S HCl
    Chemical Name:
    (S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochloride
    Molecular Weight:
    458.90
    Molecular Formula:
    C17H26N8O5 &bul; HCl
    Solubility:
    Soluble in Water (greater than 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $80.00
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  • Celastrol | Proteasome inhibitor

    CAS:
    34157-83-0
    Catalog Number:
    10-2187
    Activity:
    Proteasome inhibitor
    Chemical Name:
    (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid
    Molecular Weight:
    450.62
    Molecular Formula:
    C29H38O4
    Solubility:
    Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 30 mg/ml).
    Physical Properties:
    Red Solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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