DNA Damage/Repair
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Rucaparib phosphate | PARP1 inhibitor
From $70.00CAS:459868-92-9Catalog Number:10-3321Activity:PARP1 inhibitorChemical Name:8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-oneAlternate Name:AG-14699; PF01367338Molecular Weight:421.36Molecular Formula:C19H18FN3O • H3PO4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
SN-38 | DNA topoisomerase I inhibitor
From $75.00CAS:86639-52-3Catalog Number:10-2425Activity:DNA topoisomerase I inhibitorChemical Name:7-Ethyl-10-hydroxycamptothecinMolecular Weight:392.41Molecular Formula:C22H20N2O5Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
ß-Lapachone | Topoisomerase-1 inhibitor
From $52.00CAS:4707-32-8Catalog Number:10-2386Activity:Topoisomerase I inhibitorChemical Name:3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dioneAlternate Name:NSC-26326Molecular Weight:242.27Molecular Formula:C15H14O3Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)Physical Properties:Orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
SU0268 | OGG1 inhibitor
From $75.00CAS:2210228-45-6Catalog Number:10-4700Activity:OGG1 InhibitorChemical Names:3-[4-[[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]sulfamoyl]phenyl]benzamideMolecular Weight:475.56Molecular Formula:C26H25N3O4SSolubility:Soluble in DMSO (10 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
