Immuno-oncology
-
Prochlorperazine maleate | Endocytosis inhibitor
From $55.00CAS:84-02-6Catalog Number:10-3474Activity:Endocytosis inhibitorChemical Name:2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine dimaleateMolecular Weight:606.09Molecular Formula:C20H24ClN3S • 2C4H4O4Solubility:Soluble in DMSO (up to 15 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20° (des.)Stability:Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
R428 | Potent and selective AXL inhibitor
From $75.00CAS:1037624-75-1Catalog Number:10-4676Activity:Potent and selective AXL inhibitorChemical Name:1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamineAlternate Names:Bemcentinib; BGB324Molecular Weight:506.64Molecular Formula:C30H34N8Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Rapamycin | mTOR inhibitor
From $52.00CAS:53123-88-9Catalog Number:10-1104Activity:mTOR inhibitorAlternate Names:SirolimusMolecular Weight:914.17Molecular Formula:C51H79NO13Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 90 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Resiquimod | TLR7/8 agonist / Immune adjuvant
From $65.00CAS:144875-48-9Catalog Number:10-2733Activity:TLR7/8 agonist / Immune adjuvantChemical Name:1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-olAlternate Names:R848Molecular Weight:314.39Molecular Formula:C17H22N4O2Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml with warming)Physical Properties:White solidPurity:>98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
