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Immuno-oncology

  • Talabostat mesylate | Pyroptosis inducer / Inflammasome activator

    CAS:
    150080-09-4
    Catalog Number:
    10-4005
    Activity:
    Pyroptosis inducer / Inflammasome activator
    Chemical Name:
    ((2R)-1-((2S)-2-Amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic acid methanesulfonate
    Alternate Names:
    Val-boroPro; PT-100
    Molecular Weight:
    310.18
    Molecular Formula:
    C9H19BN2O3 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Trametinib | MEK inhibitor

    CAS:
    871700-17-3
    Catalog Number:
    10-4759
    Activity:
    MEK inhibitor
    Chemical Name:
    N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide
    Alternate Names:
    GSK1120212
    Molecular Weight:
    615.39
    Molecular Formula:
    C26H23FIN5O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • URMC-099 | MLK3 inhibitor

    CAS:
    1229582-33-5
    Catalog Number:
    10-4012
    Activity:
    MLK3 inhibitor
    Chemical Names:
    3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine
    Molecular Weight:
    421.54
    Molecular Formula:
    C27H27N5
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • WP1066 | JAK2/STAT3 inhibitor

    CAS:
    857064-38-1
    Catalog Number:
    10-4831
    Activity:
    JAK2/STAT3 inhibitor
    Chemical Name:
    (E)-3-(6-Pyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide
    Molecular Weight:
    356.22
    Molecular Formula:
    C17H14BrN3O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $79.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • α-Mangostin | STING agonist (human)

    CAS:
    6147-11-1
    Catalog Number:
    10-3433
    Activity:
    STING agonist (human)
    Chemical Name:
    1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
    Alternate Names:
    Mangostine; Mangostin
    Molecular Weight:
    410.46
    Molecular Formula:
    C24H26O6
    Solubility:
    Soluble in DMSO (up to 50 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
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