Immuno-oncology

  • Ibrutinib | BTK inhibitor

    CAS:
    936563-96-1
    Catalog Number:
    10-4757
    Alternate Name:
    PCI-32765
    Activity:
    BTK inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
    Molecular Weight:
    440.51
    Molecular Formula:
    C25H24N6O2
    Solubility:
    Soluble in DMSO ( up to at least 25 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Idelalisib | Selective PI3Kδ Inhibitor

    CAS:
    870281-82-6
    Catalog Number:
    10-4820
    Activity:
    Selective PI3Kδ Inhibitor
    Chemical Name:
    5-Fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
    Alternate Names:
    CAL-101
    Molecular Weight:
    415.43
    Molecular Formula:
    C21H18FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • Imiquimod | TLR7 Agonist

    CAS:
    99011-02-6
    Catalog Number:
    10-4230
    Alternate Name:
    R837
    Activity:
    TLR7 agonist
    Chemical Name:
    1-(2-Methylpropyl)imidazo[4,5-c]quinolin-4-amine
    Molecular Weight:
    240.30
    Molecular Formula:
    C14H16N4
    Solubility:
    Soluble in DMSO (2 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Indoximod | IDO modulator / tryptophan mimetic

    CAS:
    110117-83-4
    Catalog Number:
    10-4569
    Activity:
    IDO modulator / tryptophan mimetic
    Chemical Name:
    1-Methyl-D-tryptophan
    Molecular Weight:
    218.25
    Molecular Formula:
    C12H14N2O2
    Solubility:
    Soluble in DMSO (greater than 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98%
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
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  • Ingenol-3-angelate | PKC activator

    CAS:
    75567-37-2
    Catalog Number:
    10-1244
    Activity:
    PKC activator
    Alternate Names:
    PEP-005
    Molecular Weight:
    460.53
    Molecular Formula:
    C25H34O6
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 4 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $110.00
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