Kinases

  • RO-3306 | Selective CDK1 inhibitor

    CAS:
    872573-93-8
    Catalog Number:
    10-4126
    Activity:
    Selective CDK1 inhibitor
    Chemical Name:
    5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone
    Molecular Weight:
    351.45
    Molecular Formula:
    C18H13N3OS2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Off-white or pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Roscovitine | p34/cdc2 inhibitor

    CAS:
    186692-46-6
    Catalog Number:
    10-1332
    Activity:
    p34/cdc2 inhibitor
    Chemical Name:
    (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol
    Molecular Weight:
    354.46
    Molecular Formula:
    C19H26N6O
    Solubility:
    Soluble in DMSO (up to 10 mg/ml, with warming) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Ruxolitinib | JAK inhibitor

    CAS:
    941678-49-5
    Catalog Number:
    10-4511
    Activity:
    JAK inhibitor
    Alternate Names:
    INCB 018424
    Chemical Name:
    βR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
    Molecular Weight:
    306.37
    Molecular Formula:
    C17H18N6
    Solubility:
    Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Saracatinib | Src family kinase inhibitor

    CAS:
    379231-04-6
    Catalog Number:
    10-2901
    Activity:
    Src family kinase inhibitor
    Chemical Names:
    N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine; AZD0530
    Molecular Weight:
    542.03
    Molecular Formula:
    C27H32ClN5O5
    Solubility:
    Soluble in DMSO (50 mg/ml) and ethanol (54 mg/mL with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • SB-525334 | ALK5 inhibitor

    CAS:
    356559-20-1
    Catalog Number:
    10-2983
    Activity:
    ALK5 (TGFβR1) inhibitor
    Chemical Name:
    6-[2-(1,1-Dimethylethyl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-4-yl]quinoxaline
    Molecular Weight:
    343.42
    Molecular Formula:
    C21H21N5
    Solubility:
    Soluble in DMSO (up tp 30 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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