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Kinases

  • PLX4720 | Mutant B-Raf inhibitor

    CAS:
    918505-84-7
    Catalog Number:
    10-5113
    Activity:
    Mutant B-Raf inhibitor
    Chemical Names:
    N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
    Molecular Weight:
    413.82
    Molecular Formula:
    C17H14ClF2N3O3S
    Solubility:
    Soluble in DMSO (30 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Ponatinib | Bcr-Abl and multikinase inhibitor

    CAS:
    943319-70-8
    Catalog Number:
    10-5064
    Activity:
    Bcr-Abl and multikinase inhibitor
    Chemical Name:
    3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide
    Alternate Name:
    AP-24534
    Molecular Weight:
    532.56
    Molecular Formula:
    C29H27F32N6O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date  of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • PP1 | Src family kinase inhibitor

    CAS:
    172889-26-8
    Catalog Number:
    10-1184
    Activity:
    Src family kinase inhibitor
    Chemical Name:
    4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
    Molecular Weight:
    281.63
    Molecular Formula:
    C16H19N5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • PP2 | Src family kinase inhibitor

    CAS:
    172889-27-9
    Catalog Number:
    10-1407
    Activity:
    Src family kinase inhibitor
    Chemical Name:
    3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
    Molecular Weight:
    301.78
    Molecular Formula:
    C15H16ClN5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • PP242 | Dual mTORC1/mTORC2 inhibitor

    CAS:
    1092351-67-1
    Catalog Number:
    10-2695
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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