Kinases Archives

Ribociclib | CDK4/6 inhibitor

CAS:

1211441-98-3

Catalog Number:

10-4807

Activity:

CDK4/6 inhibitor

Chemical Name:

7-Cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

Alternate Names:

LEE011

Molecular Weight:

434.54

Molecular Formula:

C₂₃H₃₀N₈O₃

Solubility:

Soluble in DMSO (up to 10 mg/ml)

Physical Properties:

Off-white solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $60.00
View Product This product has multiple variants. The options may be chosen on the product page
RO-3306 | Selective CDK1 inhibitor

CAS:

872573-93-8

Catalog Number:

10-4126

Activity:

Selective CDK1 inhibitor

Chemical Name:

5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone

Molecular Weight:

351.45

Molecular Formula:

C₁₈H₁₃N₃OS₂

Solubility:

Soluble in DMSO (up to 15 mg/ml)

Physical Properties:

Off-white or pale yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $70.00
View Product This product has multiple variants. The options may be chosen on the product page
Roscovitine | p34/cdc2 inhibitor

CAS:

186692-46-6

Catalog Number:

10-1332

Activity:

p34/cdc2 inhibitor

Chemical Name:

(R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol

Molecular Weight:

354.46

Molecular Formula:

C₁₉H₂₆N₆O

Solubility:

Soluble in DMSO (up to 10 mg/ml, with warming) or in Ethanol (up to 10 mg/ml).

Physical Properties:

White solid

Purity:

99% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $45.00
View Product This product has multiple variants. The options may be chosen on the product page
Ruxolitinib | JAK inhibitor

CAS:

941678-49-5

Catalog Number:

10-4511

Activity:

JAK inhibitor

Alternate Names:

INCB 018424

Chemical Name:

βR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile

Molecular Weight:

306.37

Molecular Formula:

C₁₇H₁₈N₆

Solubility:

Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).

Physical Properties:

White solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $65.00
View Product This product has multiple variants. The options may be chosen on the product page
Saracatinib | Src family kinase inhibitor

CAS:

379231-04-6

Catalog Number:

10-2901

Activity:

Src family kinase inhibitor

Chemical Names:

N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine; AZD0530

Molecular Weight:

542.03

Molecular Formula:

C₂₇H₃₂ClN₅O₅

Solubility:

Soluble in DMSO (50 mg/ml) and ethanol (54 mg/mL with warming)

Physical Properties:

White solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $40.00
View Product This product has multiple variants. The options may be chosen on the product page

Kinases

Ribociclib | CDK4/6 inhibitor

RO-3306 | Selective CDK1 inhibitor

Roscovitine | p34/cdc2 inhibitor

Ruxolitinib | JAK inhibitor

Saracatinib | Src family kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

Ribociclib | CDK4/6 inhibitor

RO-3306 | Selective CDK1 inhibitor

Roscovitine | p34/cdc2 inhibitor

Ruxolitinib | JAK inhibitor

Saracatinib | Src family kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21