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Kinases

  • Selonsertib | ASK1 inhibitor

    CAS:
    1448428-04-3
    Catalog Number:
    10-4696
    Activity:
    ASK1 inhibitor
    Chemical Names:
    5-(4-Cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl)-1,2,4-triazol-3-yl)pyridine-2-yl]benzamide
    Alternate Name:
    GS-4997
    Molecular Weight:
    445.50
    Molecular Formula:
    C24H24FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Selpercatinib chemical structure Focus Biomolecules

    Selpercatinib | Potent and selective RET kinase inhibitor

    CAS:
    2152628-33-4
    Catalog Number:
    10-4407
    View Product This product has multiple variants. The options may be chosen on the product page

  • SGC-GAK-1 | Potent and selective Cyclin G Associated Kinase (GAK) inhibitor

    CAS:
    2226517-76-4
    Catalog Number:
    10-4796
    Activity:
    Potent and selective Cyclin G Associated Kinase (GAK) inhibitor
    Chemical Name:
    6-Bromo-N-(3,4,5-trimethoxyphenyl)quinoline-4-amine
    Molecular Weight:
    389.25
    Molecular Formula:
    C18H17BrN2O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 10 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Sitravatinib | Multikinase inhibitor / Immuno-oncology agent

    CAS:
    1123837-84-2
    Catalog Number:
    10-4826
    Activity:
    Multikinase inhibitor / Immuno-oncology agent
    Chemical Name:
    1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    MGCD516
    Molecular Weight:
    629.68
    Molecular Formula:
    C33H29N5O4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • SMI-4a (CAS 438190-29-5) Chemical Structure

    SMI-4a | PIM1 inhibitor

    CAS:
    438190-29-5
    Catalog Number:
    10-1359
    Activity:
    PIM1 inhibitor
    Chemical Name:
    5-(3-Trifluoromethylbenzylidene)thiazolidine
    Molecular Weight:
    273.23
    Molecular Formula:
    C11H6F3NO2S
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

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Plymouth Meeting, PA USA
1-855-FOCUS21

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