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Kinases

  • SGC-GAK-1 | Potent and selective Cyclin G Associated Kinase (GAK) inhibitor

    CAS:
    2226517-76-4
    Catalog Number:
    10-4796
    Activity:
    Potent and selective Cyclin G Associated Kinase (GAK) inhibitor
    Chemical Name:
    6-Bromo-N-(3,4,5-trimethoxyphenyl)quinoline-4-amine
    Molecular Weight:
    389.25
    Molecular Formula:
    C18H17BrN2O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 10 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Sitravatinib | Multikinase inhibitor / Immuno-oncology agent

    CAS:
    1123837-84-2
    Catalog Number:
    10-4826
    Activity:
    Multikinase inhibitor / Immuno-oncology agent
    Chemical Name:
    1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    MGCD516
    Molecular Weight:
    629.68
    Molecular Formula:
    C33H29N5O4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • SMI-4a (CAS 438190-29-5) Chemical Structure

    SMI-4a | PIM1 inhibitor

    CAS:
    438190-29-5
    Catalog Number:
    10-1359
    Activity:
    PIM1 inhibitor
    Chemical Name:
    5-(3-Trifluoromethylbenzylidene)thiazolidine
    Molecular Weight:
    273.23
    Molecular Formula:
    C11H6F3NO2S
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SNS-314 mesylate | Aurora kinase inhibitor

    CAS:
    1146618-41-8
    Catalog Number:
    10-4779
    Activity:
    Aurora kinase inhibitor
    Chemical Name:
    1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea mesylate
    Molecular Weight:
    527.04
    Molecular Formula:
    C18H15ClN6OS2 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Sorafenib | Multi-kinase inhibitor

    CAS:
    284461-73-0
    Catalog Number:
    10-2174
    Activity:
    Inhibitor of Raf-1 and other kinases
    Alternate Names:
    BAY 43-9006
    Chemical Name:
    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide
    Molecular Weight:
    464.83
    Molecular Formula:
    C21H16ClF3N4O3
    Solubility:
    Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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