Kinases
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ERGi-USU | Highly Selective ERG Inhibitor
From $35.00CAS:1147-56-4Catalog Number:10-4290Activity:Highly selective ERG inhibitorChemical Name:1-(2-Thiazolylazo)-2-naphtholAlternate Names:NSC139021Molecular Weight:255.30Molecular Formula:C13H9N3OSSolubility:Soluble in DMSO (up to at least 10 mg/ml)Physical Properties:Red or orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Erlotinib HCl | EGFR Kinase inhibitor
From $35.00CAS:183319-69-9Catalog Number:10-2135Activity:EGFR Kinase inhibitorChemical Name:N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochlorideMolecular Weight:429.91Molecular Formula:C22H23N3O4 HClSolubility:Soluble in DMSO (up to 18 mg/ml with warming).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Flavopiridol HCl | CDK inhibitor
From $50.00CAS:131740-09-5Catalog Number:10-3063Activity:CDK inhibitorChemical Name:3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochlorideAlternate Names:L 86-8275; Alvocidib; NSC-649890Molecular Weight:438.30Molecular Formula:C21H20ClNO5 &bul; HClSolubility:Soluble in DMSO (up to 40 mg/ml) or in Water (up to 40 mg/ml).Physical Properties:Light yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 monthShipping Code:RT -
Fruquintinib | Potent and selective inhibitor of VEGFR kinase
From $60.00CAS:1194506-26-7Catalog Number:10-4784Activity:Potent and selective inhibitor of VEGFR kinaseChemical Name:6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamideAlternate Name:HMPL-013Molecular Weight:393.40Molecular Formula:C21H19N3O5Solubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic
From $45.00CAS:700874-72-2Catalog Number:10-4110Activity:Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeuticChemical Name:4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamideAlternate Names:LY2157299Molecular Weight:369.43Molecular Formula:C22H19N5OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
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- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
