Kinases

  • Duvelisib | PI3Kdelta/gamma inhibitor

    CAS:
    1201438-56-3
    Catalog Number:
    10-4788
    Activity:
    PI3Kδ/γ inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one
    Alternative Name:
    IPI-145
    Molecular Weight:
    416.87
    Molecular Formula:
    C22H17ClN6O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • eFT508 | Potent MNK1/2 inhibitor

    CAS:
    1849590-01-7
    Catalog Number:
    10-4081
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  • ERGi-USU | Highly Selective ERG Inhibitor

    CAS:
    1147-56-4
    Catalog Number:
    10-4290
    Activity:
    Highly selective ERG inhibitor
    Chemical Name:
    1-(2-Thiazolylazo)-2-naphthol
    Alternate Names:
    NSC139021
    Molecular Weight:
    255.30
    Molecular Formula:
    C13H9N3OS
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    Red or orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $35.00
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  • Erlotinib HCl | EGFR Kinase inhibitor

    CAS:
    183319-69-9
    Catalog Number:
    10-2135
    Activity:
    EGFR Kinase inhibitor
    Chemical Name:
    N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
    Molecular Weight:
    429.91
    Molecular Formula:
    C22H23N3O4 HCl
    Solubility:
    Soluble in DMSO (up to 18 mg/ml with warming).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $35.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Flavopiridol HCl | CDK inhibitor

    CAS:
    131740-09-5
    Catalog Number:
    10-3063
    Activity:
    CDK inhibitor
    Chemical Name:
    3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochloride
    Alternate Names:
    L 86-8275; Alvocidib; NSC-649890
    Molecular Weight:
    438.30
    Molecular Formula:
    C21H20ClNO5 &bul; HCl
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Water (up to 40 mg/ml).
    Physical Properties:
    Light yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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