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Programmed cell death

  • Nilotinib | BCR-ABL inhibitor

    CAS:
    641571-10-0
    Catalog Number:
    10-2152
    Activity:
    BCR-ABL inhibitor
    Chemical Name:
    4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
    Alternate Names:
    AMN107
    Molecular Weight:
    529.52
    Molecular Formula:
    C28H22F3N7O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Nocardamine | Iron chelator/Ferroptosis inhibitor

    CAS:
    26605-16-3
    Catalog Number:
    10-2775
    Activity:
    Iron chelator/Ferroptosis inhibitor
    Chemical Names:
    1,12,23-Trihydroxy-1,6,12,17,23,28-hexazacyclotritriacontane-2,5,13,16,24,27-hexone
    Alternate Name:
    Desferrioxamine E
    Molecular Weight:
    600.71
    Molecular Formula:
    C27H48N6O9
    Solubility:
    Soluble in DMSO (5 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    $125.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • NSC697923 | E2 ubiquitin-conjugating enzyme inhibitor

    CAS:
    343351-67-7
    Catalog Number:
    10-1418
    Activity:
    Ubiquitin E2 conjugating enzyme inhibitor
    Chemical Name:
    2-[(Methylphenyl)sulfonyl]-5-nitrofuran
    Molecular Weight:
    267.26
    Molecular Formula:
    C11H9NO5S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
    Physical Properties:
    Pink solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Nutlin-3 | p53/mdm2 inhibitor

    CAS:
    548472-68-0
    Catalog Number:
    10-1350
    Activity:
    p53/mdm2 inhibitor
    Chemical Name:
    (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
    Molecular Weight:
    581.51
    Molecular Formula:
    C30H30Cl2N4O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $100.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Obatoclax | Bcl-2 antagonist – Induces apoptosis

    CAS:
    803712-79-0
    Catalog Number:
    10-2660
    Activity:
    BCL-2 antagonist – Induces apoptosis
    Alternate Names:
    GX15-070
    Chemical Name:
    2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate
    Molecular Weight:
    413.5
    Molecular Formula:
    C20H19N3O CH3SO3H
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    Purple solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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