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Programmed cell death

  • MLN4924 | NEDD8 activating enzyme inhibitor

    CAS:
    905579-51-3
    Catalog Number:
    10-1311
    Activity:
    NEDD8 activating enzyme inhibitor
    Chemical Name:
    ((1S,2S,4R)-4-(4-(((S)-2,3-Dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate; Pevonedistat
    Molecular Weight:
    443.53
    Molecular Formula:
    C21H25N5O4S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • MOMIPP | Methuosis inducer

    CAS:
    1363421-46-8
    Catalog Number:
    10-4766
    Activity:
    Methuosis Inducer
    Chemical Names:
    trans-3-(5-Methoxy-2-methyl-1H-indol-3-yl)-1-(4-pyridinyl)-2-propen-1-one
    Molecular Weight:
    292.33
    Molecular Formula:
    C18H16N2O2
    Solubility:
    Soluble in DMSO (7 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Necrosulfonamide | Necroptosis inhibitor / MLKL inhibitor

    CAS:
    1360614-48-7
    Catalog Number:
    10-4860
    Activity:
    Necroptosis inhibitor / MLKL inhibitor
    Chemical Name:
    (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
    Molecular Weight:
    461.47
    Molecular Formula:
    C18H15N5O6S2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Nilotinib | BCR-ABL inhibitor

    CAS:
    641571-10-0
    Catalog Number:
    10-2152
    Activity:
    BCR-ABL inhibitor
    Chemical Name:
    4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
    Alternate Names:
    AMN107
    Molecular Weight:
    529.52
    Molecular Formula:
    C28H22F3N7O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Nocardamine | Iron chelator/Ferroptosis inhibitor

    CAS:
    26605-16-3
    Catalog Number:
    10-2775
    Activity:
    Iron chelator/Ferroptosis inhibitor
    Chemical Names:
    1,12,23-Trihydroxy-1,6,12,17,23,28-hexazacyclotritriacontane-2,5,13,16,24,27-hexone
    Alternate Name:
    Desferrioxamine E
    Molecular Weight:
    600.71
    Molecular Formula:
    C27H48N6O9
    Solubility:
    Soluble in DMSO (5 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    $125.00
    View Product This product has multiple variants. The options may be chosen on the product page
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