Programmed cell death

  • SB-225002 | CXCR2 antagonist

    CAS:
    182498-32-4
    Catalog Number:
    10-2850
    Activity:
    CXCR2 antagonist
    Chemical Name:
    N-(2-Bromophenyl)-N’-(2-hydroxy-4-nitrophenyl)urea
    Molecular Weight:
    352.14
    Molecular Formula:
    C13H10BrN3O4
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Seriniquinone | Autophagy inducer

    Catalog Number:
    10-1608
    CAS #:
    22200-69-7
    Activity:
    Autophagy inducer
    Chemical Name:
    Dinaphthol[2,3-b:2’,3’-d]thiophene-5,7,12,13-tetraone
    Molecular Weight:
    344.34
    Molecular Formula:
    C20H8O4S
    Solubility:
    Soluble in DMSO (up to 15 mg/ml with warming) or in DMF (up to 15 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • SHP099 | SHP2 inhibitor

    CAS:
    1801747-11-4
    Catalog Number:
    10-4604
    Activity:
    SHP2 inhibitor
    Chemical Name:
    6-(4-Amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine dihydrochloride
    Molecular Weight:
    425.18
    Molecular Formula:
    C16H19Cl2N5 • 2HCl
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in water (up to at least 20 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Siramesine | Selective sigma-2 agonist

    CAS:
    147817-50-3
    Catalog Number:
    10-4202
    Activity:
    Selective sigma-2 agonist
    Chemical Name:
    1’-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4’-piperidine;
    Alternate Names:
    Lu 28-179
    Molecular Weight:
    454.59
    Molecular Formula:
    C30H31FN2O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • SM-164 | Smac mimetic

    CAS:
    957135-43-2
    Catalog Number:
    10-5464
    Activity:
    Smac mimetic
    Chemical Names:
    (3S,3′S,6S,6′S,10aS,10′aS)-N,N′-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamide
    Molecular Weight:
    1121.45
    Molecular Formula:
    C62H84N14O6
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    White to pale-yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $190.00
    View Product This product has multiple variants. The options may be chosen on the product page
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