Programmed cell death Archives

SHP099 | SHP2 inhibitor

CAS:

180747-42-4

Catalog Number:

10-4604

Activity:

SHP2 inhibitor

Chemical Name:

6-(4-Amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine dihydrochloride

Molecular Weight:

425.18

Molecular Formula:

C₁₆H₁₉Cl₂N₅ • 2HCl

Solubility:

Soluble in DMSO (up to 5 mg/ml) or in water (up to at least 20 mg/ml)

Physical Properties:

Yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $75.00
View Product This product has multiple variants. The options may be chosen on the product page
Siramesine | Selective sigma-2 agonist

CAS:

147817-50-3

Catalog Number:

10-4202

Activity:

Selective sigma-2 agonist

Chemical Name:

1’-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4’-piperidine;

Alternate Names:

Lu 28-179

Molecular Weight:

454.59

Molecular Formula:

C₃₀H₃₁FN₂O

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $70.00
View Product This product has multiple variants. The options may be chosen on the product page
SM-164 | Smac mimetic

CAS:

957135-43-2

Catalog Number:

10-5464

Activity:

Smac mimetic

Chemical Names:

(3S,3′S,6S,6′S,10aS,10′aS)-N,N′-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamide

Molecular Weight:

1121.45

Molecular Formula:

C₆₂H₈₄N₁₄O₆

Solubility:

Soluble in DMSO (50 mg/ml)

Physical Properties:

White to pale-yellow solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $190.00
View Product This product has multiple variants. The options may be chosen on the product page
Sorafenib | Multi-kinase inhibitor

CAS:

475207-59-1

Catalog Number:

10-2174

Activity:

Inhibitor of Raf-1 and other kinases

Alternate Names:

BAY 43-9006

Chemical Name:

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

Molecular Weight:

464.83

Molecular Formula:

C₂₁H₁₆ClF₃N₄O₃

Solubility:

Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml).

Physical Properties:

Off-white solid

Purity:

99% by TLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $40.00
View Product This product has multiple variants. The options may be chosen on the product page
SP2509 | LSD1 inhibitor

CAS:

1423715-09-6

Catalog Number:

10-4019

Activity:

LSD1 inhibitor

Chemical Name:

(E)-N’-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-(morpholinosulfonyl)benzohydrazide

Molecular Weight:

437.90

Molecular Formula:

C₁₉H₂₀ClN₃O₅S

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $75.00
View Product This product has multiple variants. The options may be chosen on the product page

Programmed cell death

SHP099 | SHP2 inhibitor

Siramesine | Selective sigma-2 agonist

SM-164 | Smac mimetic

Sorafenib | Multi-kinase inhibitor

SP2509 | LSD1 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Programmed cell death

SHP099 | SHP2 inhibitor

Siramesine | Selective sigma-2 agonist

SM-164 | Smac mimetic

Sorafenib | Multi-kinase inhibitor

SP2509 | LSD1 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21