Ubiquitin proteasome
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ML323 | USP-1/UAF-1 inhibitor
From $85.00CAS:1572414-83-5Catalog Number:10-1560Activity:USP-1/UAF-1 inhibitorChemical Name:N-(4-(1H-1,2,3-Triazol-1-yl(benzyl)-5-methyl-2-(2-isopropylphenyl)pyrimidin-4-amineAlternate Names:CID 60167849; NCGC00262306Molecular Weight:384.48Molecular Formula:C23H24N6Solubility:Soluble in DMSO (up to 40 mg/ml), or in Ethanol (up to 20 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
MLN4924 | NEDD8 activating enzyme inhibitor
From $60.00CAS:905579-51-3Catalog Number:10-1311Activity:NEDD8 activating enzyme inhibitorChemical Name:((1S,2S,4R)-4-(4-(((S)-2,3-Dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate; PevonedistatMolecular Weight:443.53Molecular Formula:C21H25N5O4SSolubility:Soluble in DMSO (up to 10 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
NAcM-OPT | NEDD8 ligation inhibitor
From $55.00CAS:2089293-61-6Catalog Number:10-1636Activity:NEDD8 ligation inhibitorChemical Name:1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3,4-dichlorophenyl)ureaMolecular Weight:434.40Molecular Formula:C23H29Cl2N3OSolubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC/TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as from date of purchase supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
NSC697923 | E2 ubiquitin-conjugating enzyme inhibitor
From $50.00CAS:343351-67-7Catalog Number:10-1418Activity:Ubiquitin E2 conjugating enzyme inhibitorChemical Name:2-[(Methylphenyl)sulfonyl]-5-nitrofuranMolecular Weight:267.26Molecular Formula:C11H9NO5SSolubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml with warming)Physical Properties:Pink solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Wnt/ß-Catenin
