DNA Damage Response
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PJ-34 HCl | PARP1/2 inhibitor
From $56.00CAS:344458-15-7Catalog Number:10-2395Activity:PARP1,2 inhibitorChemical Name:N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochlorideMolecular Weight:331.81Molecular Formula:C17H17N3O2Solubility:Soluble in DMSO (up to 30 mg/ml) or in Water (up to 20 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RT (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
RI-1 | RAD51 inhibitor
From $52.00CAS:415713-60-9Catalog Number:10-1617Activity:RAD51 inhibitorChemical Name:3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dioneMolecular Weight:361.61Molecular Formula:C14H11Cl3N2O3Solubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 10 mg/ml with warming)Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
RS-1 | RAD51 activator / CRISPR enhancer
From $50.00CAS:312756-74-4Catalog Number:10-4099Activity:RAD51 activators / CRISPR enhancerChemical Name:4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamideMolecular Weight:524.23Molecular Formula:C20H16BrN2O3SSolubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Rucaparib phosphate | PARP1 inhibitor
From $70.00CAS:459868-92-9Catalog Number:10-3321Activity:PARP1 inhibitorChemical Name:8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-oneAlternate Name:AG-14699; PF01367338Molecular Weight:421.36Molecular Formula:C19H18FN3O • H3PO4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
SN-38 | DNA topoisomerase I inhibitor
From $75.00CAS:86639-52-3Catalog Number:10-2425Activity:DNA topoisomerase I inhibitorChemical Name:7-Ethyl-10-hydroxycamptothecinMolecular Weight:392.41Molecular Formula:C22H20N2O5Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
