Transcription factors
Showing 1–12 of 82 results
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Bone and Connective Tissue
1,4-DPCA | Prolyl hydroxylase inhibitor
1,4-DPCA (331830-20-7) is a potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM).1 Inhibits collagen deposition via inhibition of collagen prolin...$42.00 – $160.00 Select options -
Cancer
10058-F4 | Myc inhibitor
10058-F4 (403811-55-2) effectively disables c-Myc by inhibiting the c-Myc-Max association and function.1 It prevents the growth of fibroblasts in a...$54.00 – $200.00 Select options -
New Products
10074-G5 | c-Myc inhibitor
10074-G5 (413611-93-5) inhibits c-Myc by disrupting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity.1 10074-G5 binds to...$55.00 – $170.00 Select options -
Antioxidants
AI-1 | Nrf2 activator
AI-1 (75483-04-4) is a novel antioxidant response element (ARE) activator which activates Nrf2 by covalently modifying Keap1 (Kelch-like ECH-associ...$70.00 – $280.00 Select options -
Antioxidants
AI-3 | ARE activator
AI-3 (882288-28-0) is an activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at C...$75.00 – $300.00 Select options -
Aurora kinase
Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc
Alisertib (MLN8237, 1028486-01-2) is a highly selective and potent (IC50 = 1 nM) cell permeable inhibitor of Aurora A with off-target binding at GA...$60.00 – $230.00 Select options -
Apoptosis
Amifostine | Cellular protectant
Amifostine (20537-88-6) is a broad spectrum radio- and chemoprotective agent.1 Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and rest...$56.00 – $224.00 Select options -
Cancer
Anacardic Acid | HAT inhibitor
Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50...$35.00 – $140.00 Select options -
Antivirals
Andrographolide | Induces mitochondrial-mediated apoptosis
Andrographolide (5508-58-7) is the major bioactive component of the medicinal plant Andrographis paniculate. Demonstrates anti-inflammatory anti-ap...$34.00 – $136.00 Select options -
Antifungals
Apicidin | HDAC inhibitor
Apicidin (183506-66-3) is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC's).1 It also displays antitumor p...$55.00 – $220.00 Select options -
Angiogenesis
Apigenin | Protein kinase inhibitor
Apigenin (520-36-5) is a plant flavonoid with antioxidant properties. It has been reported to have myriad effects on biochemical pathways including...$36.00 – $130.00 Select options -
Cancer
BAY 87-2243 | HIF-1 / Mitochondrial complex I inhibitor
BAY 87-2243 (1227158-85-1) potently inhibits HIF-1 reporter gene activity (IC50 = 0.7 nM) and CA9 protein expression (IC50 = 2.0 nM).1 It inhibited...$60.00 – $225.00 Select options
