Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Clemastine fumarate | Histamine H1 receptor antagonist/Enhances Remyelination
CAS:14976-57-9Catalog Number:10-4644 -
Clodronate 2Na | Induces osteoclast apoptosis
From $30.00CAS:88416-50-6Catalog Number:10-4631Activity:Induces osteoclast apoptosisChemical Name:Dichloromethylenediphosphonic acid disodium tetrahydrateMolecular Weight:360.92Molecular Formula:CH2Cl2O6P2·2Na·4H2OSolubility:Soluble in Water (up to at least 10 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Clozapine | Dopamine D2/D4 antagonist
From $50.00CAS:5786-21-0Catalog Number:10-1140Activity:Dopamine D2/D4 antagonistChemical Name:8-Chloro-11-(4-methyl-1-piperazinyl)-5/H-dibenzo[b,e]diazepineMolecular Weight:326.82Molecular Formula:C18H19ClN4Solubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Colchicine | Microtubule depolymerizer
From $60.00CAS:64-86-8Catalog Number:10-2310Activity:Microtubule depolymerizing agentChemical Name:(S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamideMolecular Weight:399.45Molecular Formula:C22H25NO6Solubility:Soluble in DMSO (up to 25 mg/ml), in Water (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White to pale-yellow solidPurity:99% by TLC/HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Crizotinib | c-MET and ALK inhibitor
From $80.00CAS:877399-52-5Catalog Number:10-2626Activity:c-MET and ALK inhibitorChemical Name:3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamineAlternate Names:PF-02341066, PF-1066Molecular Weight:450.34Molecular Formula:C21H22Cl2FN5OSolubility:Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Cyclosporin A | Inhibits mitochondrial permeability pore opening
From $50.00CAS:59865-13-3Catalog Number:10-1119Activity:Inhibits mitochondrial permeability pore openingMolecular Weight:1202.65Molecular Formula:C62H111N11O12Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:99% by TLCStorage Temperature:-20°CStability:Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
