Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Quinacrine HCl | Antiprotozoan / Anticancer

    CAS:
    69-05-6
    Catalog Number:
    10-4251
    Activity:
    Antiprotozoan / Anticancer
    Chemical Name:
    6-Chloro-9-(4-diethylamino-1-methylbutyl)amino-2-methoxyacridine dihydrochloride
    Molecular Weight:
    472.88
    Molecular Formula:
    C23H30ClN3O • 2HCl
    Solubility:
    Soluble in Water (up to at least 25 mg/ml) or in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Solutions in water should be made fresh daily.
    Shipping Code:
    RT
    From $30.00
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  • Ranolazine | Selective sodium channel blocker

    CAS:
    142387-99-3
    Catalog Number:
    10-3701
    Activity:
    Selective sodium channel blocker
    Chemical Name:
    (±)-N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)-propyl]piperazin-1-yl]acetamide
    Molecular Weight:
    427.54
    Molecular Formula:
    C24H33N3O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $30.00
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  • Rapamycin | mTOR inhibitor

    CAS:
    53123-88-9
    Catalog Number:
    10-1104
    Activity:
    mTOR inhibitor
    Alternate Names:
    Sirolimus
    Molecular Weight:
    914.17
    Molecular Formula:
    C51H79NO13
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 90 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years  from date of purchase as supplied.  Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $52.00
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  • Repaglinide | Kir6 blocker

    CAS:
    135062-02-1
    Catalog Number:
    10-4661
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  • Resiquimod | TLR7/8 agonist / Immune adjuvant

    CAS:
    144875-48-9
    Catalog Number:
    10-2733
    Activity:
    TLR7/8 agonist / Immune adjuvant
    Chemical Name:
    1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
    Alternate Names:
    R848
    Molecular Weight:
    314.39
    Molecular Formula:
    C17H22N4O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $65.00
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  • Retinoic acid | Retinoid RAR agonist

    CAS:
    302-79-4
    Catalog Number:
    10-1138
    Activity:
    Retinoid RAR agonist
    Alternate Names:
    ATRA
    Chemical Name:
    3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
    Molecular Weight:
    300.44
    Molecular Formula:
    C20H28O2
    Solubility:
    Soluble in DMSO (up to 8 mg/ml) or in Ethanol (up to 15 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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