Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Retinoic acid | Retinoid RAR agonist
From $30.00CAS:302-79-4Catalog Number:10-1138Activity:Retinoid RAR agonistAlternate Names:ATRAChemical Name:3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acidMolecular Weight:300.44Molecular Formula:C20H28O2Solubility:Soluble in DMSO (up to 8 mg/ml) or in Ethanol (up to 15 mg/ml).Physical Properties:Yellow solidPurity:98%
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ribavirin | Antiviral guanosine ribonucleoside analog
From $35.00CAS:36791-04-5Catalog Number:10-1281Activity:Antiviral guanosine ribonucleoside analogChemical Name:1-(β-D-Ribofuranosyl)-1H-1,2,4-triazole-3-carboxamideMolecular Weight:244.21Molecular Formula:C8H12N4O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 25 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Ribociclib | CDK4/6 inhibitor
From $60.00CAS:1211441-98-3Catalog Number:10-4807Activity:CDK4/6 inhibitorChemical Name:7-Cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamideAlternate Names:LEE011Molecular Weight:434.54Molecular Formula:C23H30N8O3Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Riluzole | Sodium channel blocker / Neuroprotective
From $38.00CAS:1744-22-5Catalog Number:10-2815Activity:Sodium channel blocker / NeuroprotectiveChemical Name:2-Amino-6-(trifluoromethoxy)benzothiazoleMolecular Weight:234.20Molecular Formula:C8H5F3N2OSSolubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Ritonavir | HIV1/2 protease inhibitor
From $40.00CAS:155213-67-5Catalog Number:10-4484Activity:HIV 1/2 protease inhibitorChemical Name:1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-2-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamateMolecular Weight:720.95Molecular Formula:C37H48N5O5S2Solubility:Soluble in DMSO (up to 12 mg/ml with warming) or in Ethanol (up to 5 mg/ml).Physical Properties:White solidPurity:98% by HPLCStorage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT -
Roflumilast | PDE4 inhibitor
From $65.00CAS:162401-32-3Catalog Number:10-2657Activity:PDE4 inhibitorChemical Name:3(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-benzamideAlternate Names:BYK-20869Molecular Weight:403.21Molecular Formula:C17H14N2Cl2F2O3Solubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
