Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Pioglitazone HCl | PPAR gamma agonist

    CAS:
    112529-15-4
    Catalog Number:
    10-1010
    Activity:
    PPARγ agonist
    Chemical Name:
    5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride
    Molecular Weight:
    392.90
    Molecular Formula:
    C19H20N2O3S·HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Pirfenidone | Antifibrotic

    CAS:
    53179-13-8
    Catalog Number:
    10-2307
    Activity:
    Antifibrotic
    Chemical Name:
    5-Methyl-1-phenyl-2(1H)-pyridinone
    Molecular Weight:
    185.23
    Molecular Formula:
    C12H11NO
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
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  • plerixafor chemical structure

    Plerixafor | CXCR4 antagonist

    CAS:
    155148-31-5
    Catalog Number:
    10-2864
    Activity:
    CXCR4 antagonist
    Molecular Weight:
    794.48
    Molecular Formula:
    C28H54N8 • 8HCl
    Solubility:
    Soluble in Water (up to at least 55 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $55.00
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  • Pranlukast chemical structure

    Pranlukast | Leukotriene CysLT1 antagonist / GPR17 antagonist

    CAS:
    103177-37-3
    Catalog Number:
    10-2441
    Activity:
    Leukotriene CysLT1 antagonist / GPR17 antagonist
    Chemical Name:
    N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide
    Alternate Names:
    ONO-1078
    Molecular Weight:
    481.51
    Molecular Formula:
    C27H23N5O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • image

    Prochlorperazine maleate | Endocytosis inhibitor

    CAS:
    84-02-6
    Catalog Number:
    10-3474
    Activity:
    Endocytosis inhibitor
    Chemical Name:
    2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine dimaleate
    Molecular Weight:
    606.09
    Molecular Formula:
    C20H24ClN3S • 2C4H4O4
    Solubility:
    Soluble in DMSO (up to 15 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • PGE1 chemical structure

    Prostaglandin E1 | Vasodilator

    CAS:
    745-65-3
    Catalog Number:
    10-4455
    Activity:
    Vasodilator
    Chemical Name:
    (11a, 13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid
    Alternate Names:
    PGE1; Alprostadil
    Molecular Weight:
    354.49
    Molecular Formula:
    C20H34O5
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    Blue Ice
    From $30.00
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