Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Pranlukast | Leukotriene CysLT1 antagonist / GPR17 antagonist
From $50.00CAS:103177-37-3Catalog Number:10-2441Activity:Leukotriene CysLT1 antagonist / GRP17 antagonistChemical Name:N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamiAlternate Names:ONO-1078Molecular Weight:481.51Molecular Formula:C27H23N5O4Solubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Prochlorperazine maleate | Endocytosis inhibitor
From $55.00CAS:84-02-6Catalog Number:10-3474Activity:Endocytosis inhibitorChemical Name:2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine dimaleateMolecular Weight:606.09Molecular Formula:C20H24ClN3S • 2C4H4O4Solubility:Soluble in DMSO (up to 15 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20° (des.)Stability:Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Prostaglandin E1 | Vasodilator
From $50.00CAS:745-65-3Catalog Number:10-4455Activity:VasodilatorChemical Name:(11a, 13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acidAlternate Names:PGE1; AlprostadilMolecular Weight:354.49Molecular Formula:C20H34O5Solubility:Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 15 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:Blue Ice -
Quetiapine hemifumarate | Atypical antipsychotic agent
From $30.00CAS:111974-72-2Catalog Number:10-2587Activity:Atypical antipsychotic agentChemical Name:2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarateAlternate Names:ICI-204636Molecular Weight:441.54Molecular Formula:C21H25N3O2 • 0.5C4H4O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Quinacrine HCl | Antiprotozoan / Anticancer
From $30.00CAS:69-05-6Catalog Number:10-4251Activity:Antiprotozoan / AnticancerChemical Name:6-Chloro-9-(4-diethylamino-1-methylbutyl)amino-2-methoxyacridine dihydrochlorideMolecular Weight:472.88Molecular Formula:C23H30ClN3O • 2HClSolubility:Soluble in Water (up to at least 25 mg/ml) or in DMSO (up to at least 10 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Solutions in water should be made fresh daily.Shipping Code:RT -
Ranolazine | Selective sodium channel blocker
From $30.00CAS:142387-99-3Catalog Number:10-3701Activity:Selective sodium channel blockerChemical Name:(±)-N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)-propyl]piperazin-1-yl]acetamideMolecular Weight:427.54Molecular Formula:C24H33N3O4Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:White solidPurity:98% by TLCStorage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT
