Kinases

  • IPA-3 | Selective inhibitor of PAK1

    CAS:
    42521-82-4
    Catalog Number:
    10-4765
    Activity:
    Selective inhibitor of PAK1
    Chemical Name:
    1,1′-Dithiodi-2-naphthol
    Molecular Weight:
    350.45
    Molecular Formula:
    C20H14O2S2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Ipatasertib | pan-Akt inhibitor

    CAS:
    1001264-89-6
    Catalog Number:
    10-4751
    Activity:
    pan-Akt inhibitor
    Chemical Names:
    (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-yla,ino)propan-1-one; GDC-0068
    Molecular Weight:
    458.00
    Molecular Formula:
    C24H32ClN5O2
    Solubility:
    Soluble in DMSO (25 mg/mL) or ethanol (20 mg/mL)
    Physical Properties:
    Off-white to pale pink solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

    CAS:
    1693758-51-8
    Catalog Number:
    10-4827
    Activity:
    Selective PI3K-gamma inhibitor / Immuno-oncology agent
    Chemical Name:
    (S)-2-Amino-N-[1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; Eganelisib
    Molecular Weight:
    629.68
    Molecular Formula:
    C30H24N8O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • JH-X-119-01 | Selective IRAK1 inhibitor

    CAS:
    2227368-54-7
    Catalog Number:
    10-4691
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  • JNK inhibitor IX | JNK inhibitor

    CAS:
    312917-14-9
    Catalog Number:
    10-1528
    Activity:
    JNK inhibitor
    Chemical Name:
    N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide
    Alternate Names:
    TCS JNK 5a
    Molecular Weight:
    332.42
    Molecular Formula:
    C20H16N2OS
    Solubility:
    Soluble in DMSO (up to 13 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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