Kinases
-
PKC-412 | Protein kinase inhibitor (pan-specific)
From $50.00CAS:120685-11-2Catalog Number:10-1105Activity:Protein kinase inhibitor (pan-specific.)Alternate Names:Midostaurin, CGP-41251Chemical Name:4′-N-BenzoylstaurosporineMolecular Weight:570.65Molecular Formula:C35H30N4O4Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 2 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
PLX4032 | BRAF inhibitor
From $40.00CAS:918504-65-1Catalog Number:10-2928Activity:BRAF inhibitorChemical Name:N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamideAlternate Names:Vemurafenib, R7204, Ro 51-85426Molecular Weight:489.92Molecular Formula:C23H18ClF2N3O3SSolubility:Soluble in DMSO (up to 100 mg/ml)Physical Properties:White or off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
PLX4720 | Mutant B-Raf inhibitor
From $55.00CAS:918505-84-7Catalog Number:10-5113Activity:Mutant B-Raf inhibitorChemical Names:N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamideMolecular Weight:413.82Molecular Formula:C17H14ClF2N3O3SSolubility:Soluble in DMSO (30 mg/ml with warming)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Ponatinib | Bcr-Abl and multikinase inhibitor
From $50.00CAS:943319-70-8Catalog Number:10-5064Activity:Bcr-Abl and multikinase inhibitorChemical Name:3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamideAlternate Name:AP-24534Molecular Weight:532.56Molecular Formula:C29H27F32N6OSolubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
PP1 | Src family kinase inhibitor
From $65.00CAS:172889-26-8Catalog Number:10-1184Activity:Src family kinase inhibitorChemical Name:4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidineMolecular Weight:281.63Molecular Formula:C16H19N5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
