Kinases
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Tozasertib | Aurora kinase inhibitor
From $50.00CAS:639089-54-6Catalog Number:10-2178Activity:Aurora kinase inhibitorAlternate Names:VX-680, MK-0457Molecular Weight:464.59Molecular Formula:C23H28N8OSSolubility:Soluble in DMSO (up to 100 mg/ml).Physical Properties:Off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Trametinib | MEK inhibitor
From $40.00CAS:871700-17-3Catalog Number:10-4759Activity:MEK inhibitorChemical Name:N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamideAlternate Names:GSK1120212Molecular Weight:615.39Molecular Formula:C26H23FIN5O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
U0126 | Selective MEK1 and MEK2 inhibitor
From $90.00CAS:109511-58-2Catalog Number:10-2179Activity:Selective MEK1 and MEK2 inhibitorChemical Name:1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadieneMolecular Weight:380.49Molecular Formula:C18H16N6S2Solubility:Soluble in DMSO (up to 200 mg/ml).Physical Properties:White solidPurity:99% by HPLCStorage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Vandetanib | VEGFR2 inhibitor
From $50.00CAS:443913-73-3Catalog Number:10-2185Activity:VEGFR2 inhibitorChemical Names:4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yl)methoxy]quinazolineAlternate Name:ZD6474Molecular Weight:475.35Molecular Formula:C22H24BrFN4O2Solubility:Soluble in DMSO (30 mg/ml); Ethanol (10 mg/ml with warming)Physical Properties:White to off-white solidPurity:98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Vatalanib 2HCl | VEGFR kinase inhibitor
From $50.00CAS:212141-51-0Catalog Number:10-2183Activity:VEGFRK inhibitorChemical Name:N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochlorideAlternate Names:CGP-79787; PTK-787; ZK222584Molecular Weight:419.73Molecular Formula:C20H15ClN4·2HClSolubility:Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
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- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
