Kinases Archives

Binimetinib | MEK1/2 inhibitor

CAS:

606143-89-9

Catalog Number:

10-4789

Activity:

MEK1/2 inhibitor

Chemical Name:

6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide

Alternate Names:

ARRY-162; MEK162

Molecular Weight:

441.23

Molecular Formula:

C₁₇H₁₅BrF₂N₄O₃

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $45.00
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BML283 | PKM2 activator

CAS:

562867-96-3

Catalog Number:

10-4561

Activity:

PKM2 activator

Alternate Names:

ML083

Chemical Name:

1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)piperazine

Molecular Weight:

454.51

Molecular Formula:

C₁₉H₂₂N₂O₇S₂

Solubility:

Soluble in DMSO (up to 10 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

Shipping Code:

RT

From $45.00
View Product This product has multiple variants. The options may be chosen on the product page
Bosutinib | Dual Src/Abl kinase inhibitor

CAS:

380843-75-4

Catalog Number:

10-2122

Activity:

Dual Src/Abl kinase inhibitor

Chemical Names:

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile

Alternate Name:

SKI-606

Molecular Weight:

530.45

Molecular Formula:

C₂₆H₂₉Cl₂N₅O₃

Solubility:

Soluble in DMSO (100 mg/ml); Ethanol (up to 25 mg/ml with warming)

Physical Properties:

Off-white solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $40.00
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Brigatinib | pan-ALK inhibitor

CAS:

1197953-54-0

Catalog Number:

10-5034

Activity:

pan-ALK inhibitor

Chemical Names:

5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4- pyrimidinediamine

Alternate Name:

AP26113

Molecular Weight:

584.02

Molecular Formula:

C₂₉H₃₉ClN₇O₂P

Solubility:

Soluble in DMSO (1 mg/ml with warming)

Physical Properties:

White to off-white solid

Purity:

98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page
BT2 | BCKDC kinase inhibitor

CAS:

34576-94-8

Catalog Number:

10-4717

Activity:

BCKDC kinase inhibitor

Chemical Name:

3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid

Molecular Weight:

247.10

Molecular Formula:

C₉H₄Cl₂O₂S

Solubility:

Soluble in DMSO (up to at least 20 mg/ml)

Physical Properties:

Off-white solid

Purity:

95% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page

Kinases

Binimetinib | MEK1/2 inhibitor

BML283 | PKM2 activator

Bosutinib | Dual Src/Abl kinase inhibitor

Brigatinib | pan-ALK inhibitor

BT2 | BCKDC kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

Binimetinib | MEK1/2 inhibitor

BML283 | PKM2 activator

Bosutinib | Dual Src/Abl kinase inhibitor

Brigatinib | pan-ALK inhibitor

BT2 | BCKDC kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21