DNA Damage Response
-
ME-0328 | PARP3 inhibitor
From $70.00CAS:1445251-22-8Catalog Number:10-1484Activity:PARP3 inhibitorChemical Name:3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamideMolecular Weight:321.38Molecular Formula:C19H19N3O2Solubility:Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 4 mg/ml with warming).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Mirin | Mre11-Rad50-Nbs1 inhibitor
From $50.00CAS:299953-00-7Catalog Number:10-1069Activity:Mre11-Rad50-Nbs1 inhibitorChemical Name:5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-oneMolecular Weight:220.25Molecular Formula:C10H8N2O2SSolubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:Tan solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Mitomycin C | DNA crosslinking and damaging agent
From $55.00CAS:50-07-7Catalog Number:10-1170Activity:DNA crosslinking and damaging agentChemical Name:Natural fermentation product from Streptomyces sp.Molecular Weight:334.33Molecular Formula:C15H18N4O5Solubility:Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).Physical Properties:Blue-violet solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.Shipping Code:RT -
NU7441 | DNA-PK inhibitor
From $50.00CAS:503468-95-9Catalog Number:10-4810Activity:DNA-PK inhibitorChemical Name:8-Dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-oneAlternate Name:Ku-57788Molecular Weight:413.49Molecular Formula:C25H19NO3SSolubility:Soluble in DMSO (up to 10 mg/ml with warming).Physical Properties:Off-white to beige solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Olaparib | PARP1 inhibitor
From $45.00CAS:763113-22-0Catalog Number:10-2154Activity:PARP1 inhibitorChemical Name:4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-oneAlternate Names:AZD-2281; KU-59436Molecular Weight:434.47Molecular Formula:C24H23FN4O3Solubility:Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
