PhysioProcesses

Angiogenesis

Angiogenesis is the formation of new blood vessels from existing vasculature involving migration, growth, and differentiation of endothelial cells. It requires growth factors (e.g. VEGF, TGF-β), Notch, PI3K, proteases, adhesion molecules, and other signaling components that control cell growth, differentiation, and migration. Angiogenesis occurs in normal processes such as wound healing and embryonic development, but it also plays key roles in pathologies such as cancer and inflammation.

Cytokines

  • SX-682 | CXCR1/2 inhibitor
    CAS:
    1648843-04-2
    Catalog Number:
    10-4925
    Activity:
    CXCR1/2 inhibitor
    Chemical Names:
    [2-[[5-[(4-Fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid
    Molecular Weight:
    467.20
    Molecular Formula:
    C19H14BF4N3O4S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • AZD-2098 | CCR4 antagonist
    CAS:
    566203-88-1
    Catalog Number:
    10-4262
    Activity:
    CCR4 antagonist
    Chemical Names:
    2,3-Dichloro-N-(3-methoxypyrazine-2-yl)benzenesulfonamide
    Molecular Weight:
    334.17
    Molecular Formula:
    C11H9Cl2N3O3S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white/beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • PF-4136309 | CCR2 antagonist
    CAS:
    1341224-83-6
    Catalog Number:
    10-4261
    Activity:
    CCR2 antagonist
    Chemical Name:
    N-[2-[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
    Alternate Name:
    INCB8761
    Molecular Weight:
    568.60
    Molecular Formula:
    C29H31F3N6O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • SB-225002 | CXCR2 antagonist
    CAS:
    182498-32-4
    Catalog Number:
    10-2850
    Activity:
    CXCR2 antagonist
    Chemical Name:
    N-(2-Bromophenyl)-N’-(2-hydroxy-4-nitrophenyl)urea
    Molecular Weight:
    352.14
    Molecular Formula:
    C13H10BrN3O4
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Reparixin | CXCR 1/2 allosteric antagonist
    CAS:
    266359-83-5
    Catalog Number:
    10-2527
    Activity:
    CXCR 1/2 allosteric antagonist
    Chemical Name:
    αR-Methyl-4-(2-methylpropyl)-N-(methylsulfonyl)-benzeneacetamide
    Alternate Names:
    DF 1681Y; Repertaxin
    Molecular Weight:
    283.39
    Molecular Formula:
    C14H21NO3S
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Cytokines Products

DLL4 / Notch

  • CB-103 | Notch signaling pathway inhibitor
    CAS:
    218457-67-1
    Catalog Number:
    10-4742
    Activity:
    Notch inhibitor
    Chemical Names:
    5-Amino-2-(4-tert-butylphenoxy)pyridine
    Molecular Weight:
    242.32
    Molecular Formula:
    C15H18N2O
    Solubility:
    Soluble in DMSO (>30 mg/ml)
    Physical Properties:
    Off-white to pale orange solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • IMR-1 | Notch transcriptional activation inhibitor
    CAS:
    310456-65-6
    Catalog Number:
    10-3601
    Activity:
    Notch transcriptional activation inhibitor
    Chemical Name:
    2-[2-Methoxy-4-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid ethyl ester
    Molecular Weight:
    353.41
    Molecular Formula:
    C15H15NO5S2
    Solubility:
    Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 9 mg/ml with warming).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • FLI-06 | Notch pathway inhibitor
    CAS:
    313967-18-9
    Catalog Number:
    10-1504
    Activity:
    Notch pathway inhibitor
    Molecular Weight:
    438.52
    Molecular Formula:
    C25H30N2O5
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
View All DLL4 / Notch Products

Ephrin

  • Sitravatinib | Multikinase inhibitor / Immuno-oncology agent
    CAS:
    1123837-84-2
    Catalog Number:
    10-4826
    Activity:
    Multikinase inhibitor / Immuno-oncology agent
    Chemical Name:
    1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    MGCD516
    Molecular Weight:
    629.68
    Molecular Formula:
    C33H29N5O4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Ephrin Products

Growth Factors

  • Nintedanib | VEGFR, PDGFR, and FGFR kinase inhibitor
    CAS:
    656247-17-5
    Catalog Number:
    10-3320
  • Vandetanib | VEGFR2 inhibitor
    CAS:
    443913-73-3
    Catalog Number:
    10-2185
    Activity:
    VEGFR2 inhibitor
    Chemical Names:
    4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yl)methoxy]quinazoline
    Alternate Name:
    ZD6474
    Molecular Weight:
    475.35
    Molecular Formula:
    C22H24BrFN4O2
    Solubility:
    Soluble in DMSO (30 mg/ml); Ethanol (10 mg/ml with warming)
    Physical Properties:
    White to off-white solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Lenvatinib | VEGFR inhibitor
    CAS:
    417716-92-8
    Catalog Number:
    10-3313
    Activity:
    VEGFR inhibitor
    Chemical Name:
    4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
    Alternate Names:
    E7080
    Molecular Weight:
    426.85
    Molecular Formula:
    C21H19ClN4O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Herboxidiene | Spliceosome inhibitor
    CAS:
    142861-00-5
    Catalog Number:
    10-1614
    Activity:
    Spliceosome inhibitor
    Alternate Names:
    GEX1A
    Molecular Weight:
    438.60
    Molecular Formula:
    C25H42O6
    Solubility:
    Soluble in DMSO or Ethanol
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • PD173074 | FGFR inhibitor
    CAS:
    219580-11-7
    Catalog Number:
    10-4505
    Activity:
    FGFR inhibitor
    Chemical Name:
    1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)urea
    Molecular Weight:
    523.67
    Molecular Formula:
    C28H41N7O3
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    Yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Growth Factors Products

HIF

  • Roxadustat | Prolyl hydroxylase domain inhibitor / HIF stabilizer
    CAS:
    808118-40-3
    Catalog Number:
    10-4468
    Activity:
    Prolyl hydroxylase domain inhibitor / HIF stabilizer
    Chemical Name:
    2-[(4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
    Alternate Name:
    FG-4592
    Molecular Weight:
    352.35
    Molecular Formula:
    C19H16N2O5
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white or white solid
    Purity:
    99% by HPLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • BAY 87-2243 | HIF-1 / Mitochondrial complex I inhibitor
    CAS:
    1227158-85-1
    Catalog Number:
    10-4910
    Activity:
    HIF-1 / Mitochondrial complex I inhibitor
    Chemical Name:
    5-[1-[[2-(4-Cyclopropylpiperazin-1-yl)pyridin-4-yl]methyl]-5-methylpyrazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole
    Molecular Weight:
    525.54
    Molecular Formula:
    C26H26F3N7O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
  • KC7F2 | HIF-1α inhibitor
    CAS:
    927822-86-4
    Catalog Number:
    10-4714
    Activity:
    HIF-1alpha inhibitor
    Chemical Name:
    N,N’-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide
    Molecular Weight:
    570.38
    Molecular Formula:
    C16H16Cl4N2O4S4
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Herboxidiene | Spliceosome inhibitor
    CAS:
    142861-00-5
    Catalog Number:
    10-1614
    Activity:
    Spliceosome inhibitor
    Alternate Names:
    GEX1A
    Molecular Weight:
    438.60
    Molecular Formula:
    C25H42O6
    Solubility:
    Soluble in DMSO or Ethanol
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • HIF-2α-I2 | HIF-2α antagonist
    CAS:
    1422955-31-4
    Catalog Number:
    10-1508
    Activity:
    Hif-2α antagonist
    Chemical Name:
    N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
    Alternate Names:
    TC-S 7009
    Molecular Weight:
    308.65
    Molecular Formula:
    C12H6ClFN4O3
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 35 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All HIF Products

Integrins

View All Integrins Products

Metalloproteases

  • Doxycycline monohydrate | Broad spectrum antibiotic
    CAS:
    17086-28-1
    Catalog Number:
    10-3765
  • Batimastat | Matrix metalloprotease inhibitor (pan-specific)
    CAS:
    130370-60-4
    Catalog Number:
    10-1589
    Activity:
    Matrix metalloproteinase inhibitor (pan-specific)
    Chemical Name:
    (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamine)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
    Alternate Names:
    BB-94
    Molecular Weight:
    477.64
    Molecular Formula:
    C23H31N3O4S2
    Solubility:
    Soluble in DMSO (up to 45 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • 1,10-Phenanthroline HCl | Zn metalloprotease inhibitor
    CAS:
    18851-33-7
    Catalog Number:
    10-3017
    Activity:
    Zn metalloprotease inhibitor
    Alternate Names:
    o-Phenanthroline hydrochloride hydrate
    Molecular Weight:
    234.68
    Molecular Formula:
    C13H8N2 • HCl &bul; H2O
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Water (up to 2 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • NSC405020 | MT-MMP inhibitor
    CAS:
    7497-07-6
    Catalog Number:
    10-1462
    Activity:
    MT-MMP inhibitor
    Chemical Name:
    3,4-Dichloro-N-(1-methylbutyl)benzamide
    Molecular Weight:
    260.15
    Molecular Formula:
    C12H15NCl2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Ilomastat (GM-6001) | MMP inhibitor
    CAS:
    142880-36-2
    Catalog Number:
    10-1339
    Activity:
    MMP inhibitor
    Alternate Names:
    GM-6001
    Chemical Name:
    N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide
    Molecular Weight:
    388.46
    Molecular Formula:
    C20H28N4O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Metalloproteases Products

MetAP2

  • Fumagillin | MetAP-2 inhibitor
    CAS:
    23110-15-8
    Catalog Number:
    10-1146
    Activity:
    MetAP-2 inhibitor
    Chemical Name:
    (2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid ester
    Molecular Weight:
    458.54
    Molecular Formula:
    C26H34>/sub>O7
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Orange solid
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All MetAP2 Products

Nitric oxide

  • Carboxy-PTIO Potassium Salt | Nitric oxide scavenger
    CAS:
    148819-94-7
    Catalog Number:
    10-3037
    Activity:
    Nitric oxide scavenger
    Chemical Names:

    2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, potassium salt

    Molecular Weight:
    315.39
    Molecular Formula:
    C14H16KN2O4
    Solubility:
    Soluble in Water (up to 100 mg/ml) or in DMSO (up to 50 mg/ml)
    Physical Properties:
    Blue solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • DEA NONOate | NO Donor
    CAS:
    372965-00-9
    Catalog Number:
    10-4547
    Activity:
    NO Donor
    Chemical Name:
    2-(N,N-Diethylamino)-diazenolate-2-oxide diethylammonium salt
    Molecular Weight:
    206.29
    Molecular Formula:
    C4H10N3O2 • C4H12N
    Solubility:
    Soluble in Water or Ethanol
    Physical Properties:
    Off-white solid
    Purity:
    97% by NMR
    (1H-NMR)
    Storage Temperature:
    -80°C
    Stability:
    Stable for 1 year from date of purchase s supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use. See the product description for information on half-life in solution.
    Shipping Code:
    Blue Ice
  • Spermine NONOate | NO Donor
    CAS:
    136587-13-8
    Catalog Number:
    10-4549
    Activity:
    NO Donor
    Chemical Name:
    1-{N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino}-diazen-1-ium-1,2-diolate
    Molecular Weight:
    262.35
    Molecular Formula:
    C10H26N6O2
    Solubility:
    Soluble in Water or Ethanol
    Physical Properties:
    Off-white solid
    Purity:
    97% by (1H-NMR)
    Storage Temperature:
    -80°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use.
    Shipping Code:
    Blue Ice
  • PAPA NONOate | NO Donor
    CAS:
    146672-58-4
    Catalog Number:
    10-4548
    Activity:
    NO Donor
    Chemical Name:
    N-[3-Aminopropyl(propyl)amino]-N-hydroxynitrous amide
    Molecular Weight:
    176.22
    Molecular Formula:
    C6H16N4O2
    Solubility:
    Soluble in Water or Ethanol.
    Physical Properties:
    Off-white solid
    Purity:
    97% by (1H-NMR)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use.
    Shipping Code:
    Blue Ice
  • DETA NONOate | NO Donor
    CAS:
    146724-94-9
    Catalog Number:
    10-4527
    Activity:
    NO Donor
    Alternate Names:
    Diethylenetriamine NONOate
    Chemical Name:
    N-[bis(2-Aminoethyl)amino]-N-hydroxynitrus amide
    Molecular Weight:
    163.18
    Molecular Formula:
    C4H13N5O2
    Solubility:
    Soluble in Water.
    Physical Properties:
    Solid
    Purity:
    97% by (1H-NMR)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Store under inert gas. Solutions must be made fresh immediately before use and cannot be stored.
    Shipping Code:
    Blue Ice
View All Nitric oxide Products

Other Angiogenesis

  • Muscone | Cardioprotective and neuroprotective agent
    CAS:
    541-91-3
    Catalog Number:
    10-2757
  • Halofuginone HBr | Prolyl-tRNA synthetase inhibitor
    CAS:
    64924-67-0
    Catalog Number:
    10-2381
  • FAK inhibitor 14 | FAK inhibitor
    CAS:
    4506-66-5
    Catalog Number:
    10-2547
    Activity:
    FAK inhibitor
    Alternate Names:
    Y15
    Chemical Name:
    1,2,4,5-Benzenetetramine tetrahydrochloride
    Molecular Weight:
    284.02
    Molecular Formula:
    C6H10N4 4HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 15 mg/ml).
    Physical Properties:
    Grey solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Pomalidomide | Cereblon ubiquitination inhibitor
    CAS:
    19171-19-8
    Catalog Number:
    10-2768
    Activity:
    Cereblon ubiquination inhibitor
    Chemical Name:
    1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; 3-amino-N-(2,6-dioxo-3-piperidyl)phthalamide
    Molecular Weight:
    273.24
    Molecular Formula:
    C13H11N3O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Curcumin | Antiinflammatory
    CAS:
    458-37-7
    Catalog Number:
    10-2475
    Activity:
    Antiinflammatory
    Chemical Name:
    (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
    Alternate Names:
    Diferuloylmethane
    Molecular Weight:
    368.38
    Molecular Formula:
    C21H20O6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    90% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
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YAP/TAZ

  • PY-60 | YAP Activator
    CAS:
    2765218-56-0
    Catalog Number:
    10-3924
  • Verteporfen | YAP Inhibitor
    CAS:
    129497-78-5
    Catalog Number:
    10-3487
    Activity:
    YAP inhibitor
    Chemical Names:
    (4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
    Alternate Name:
    CL 318,952; BPD-MA
    Molecular Weight:
    718.79
    Molecular Formula:
    C41H42N4O8
    Solubility:
    Soluble in DMSO (up to 14 mg/ml)
    Physical Properties:
    Black solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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