Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Flumazenil | Benzodiazepine antagonist

    CAS:
    78755-81-4
    Catalog Number:
    10-1081
    Activity:
    Benzodiazepine antagonist
    Chemical Name:

    8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester

    Alternate Names:

    Ro 1722;  Ro 15-1788

    Molecular Weight:
    303.29
    Molecular Formula:
    C15H14FN3O3
    Solubility:
    Soluble in DMSO (up to 8 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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  • Fluoxetine HCl | Serotonin reuptake inhibitor

    CAS:
    56296-78-7
    Catalog Number:
    10-2728
    Activity:
    Serotonin reuptake inhibitor
    Chemical Name:
    (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride
    Alternate Names:
    LY-110,140
    Molecular Weight:
    345-79
    Molecular Formula:
    C17H18F3NO • HCl
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Water (up to 4 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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  • Fluvastatin Na | HMG CoA reductase inhibitor

    CAS:
    93957-55-2
    Catalog Number:
    10-2554
    Activity:
    HMG CoA reductase inhibitor
    Chemical Name:
    (+/-)(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
    Molecular Weight:
    466.45
    Molecular Formula:
    C24H25FNO4 . Na
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Water (up to 10 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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  • Formoterol hemifumarate | ß2 adrenergic agonist

    CAS:
    43229-80-7
    Catalog Number:
    10-5092
    Activity:
    Potent and selective β2 adrenergic agonist
    Chemical Name:
    (R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl] formamide
    Molecular Weight:
    402.44
    Molecular Formula:
    C19H24N2O4·1/2C4H4O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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  • FTY720 HCl | Sphingosine-1-phosphate receptor agonist

    CAS:
    162359-56-0
    Catalog Number:
    10-2138
    Activity:
    Sphingosine-1-phosphate receptor agonist
    Alternate Names:
    Fingolimod
    Chemical Name:
    2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride
    Molecular Weight:
    343.94
    Molecular Formula:
    C19H33NO2 HCl
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
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  • Fulvestrant | Estrogen receptor antagonist

    CAS:
    129453-61-8
    Catalog Number:
    10-2541
    Activity:
    Estrogen receptor antagonist
    Chemical Names:
    7α,17β-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol; ICI- 182,780; ZD-9238
    Molecular Weight:
    606.77
    Molecular Formula:
    C32H47F5O3S
    Solubility:
    Soluble in DMSO (60 mg/mL); Ethanol (30 mg/mL)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $62.00
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