Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Galanthamine HBr | Acetylcholinesterase inhibitor
From $40.00CAS:17991Catalog Number:10-1136Activity:Acetylcholinesterase inhibitorChemical Name:4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol, hydrobromideMolecular Weight:368.27Molecular Formula:C17H21NO3 HBrSolubility:Soluble in DMSO (up to 10 mg/ml) or in Water (up to 12 mg/ml).Physical Properties:Lyophillized solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Gefitinib | EGFR kinase inhibitor
From $30.00CAS:184475-35-2Catalog Number:10-1148Activity:EGFR-Kinase inhibitorAlternate Names:ZD1839, IressaChemical Name:N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amineMolecular Weight:446.91Molecular Formula:C22H24ClFN4O3Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).Physical Properties:Tan solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Gemcitabine HCl | DNA polymerase inhibitor
From $40.00CAS:122111-03-9Catalog Number:10-2140Activity:DNA polymerase inhibitorAlternate Names:dFdCChemical Name:2′-Deoxy-2′,2′-difluorocytidine hydrochlorideMolecular Weight:299.66Molecular Formula:C9H11F2N3O4 HClSolubility:Soluble in DMSO (up to 20 mg/ml) or in Water (up to 25 mg/ml).Physical Properties:White solidPurity:98%Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
Gilteritinib | FLT3 Inhibitor
From $45.00CAS:1254053-43-4Catalog Number:10-4170Activity:FLT3 inhibitorChemical Names:6-Ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide; ASP2215Molecular Weight:552.72Molecular Formula:C29H44N8O3Solubility:Soluble in DMSO (25 mg/ml)Physical Properties:Off-white to pale pink solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Gimeracil | Dihydropyrimidine dehydrogenase inhibitor
From $50.00CAS:103766-25-2Catalog Number:10-4601Activity:Dihydropyrimidine dehydrogenase inhibitorChemical Name:5-Chloro-4-hydroxypyridine-2(1H)-oneMolecular Weight:145.54Molecular Formula:C5H4ClNO2Solubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Glyburide | K-ATP channel blocker
From $30.00CAS:10238-21-8Catalog Number:10-1325Activity:K-ATP channel blockerAlternate Names:GlibenclamideChemical Name:5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]suphonyl]phenyl]ethyl]-2-methoxybenzamideMolecular Weight:494.01Molecular Formula:C23H28ClN3O5SSolubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 2 mg/ml with warming).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT
