Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Homoharringtonine | Protein synthesis inhibitor
From $60.00CAS:26833-87-4Catalog Number:10-3033Activity:Protein synthesis inhibitorChemical Names:Cephalotaxine 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioateAlternate Name:HHT; NSC141633; Omacetaxine mepesuccinateMolecular Weight:545.63Molecular Formula:C29H39NO9Solubility:Soluble in DMSO (75 mg/ml)Physical Properties:Pale yellow to off-white solidPurity:>95% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Hydroxychloroquine sulfate | Autophagy inhibitor
From $30.00CAS:747-36-4Catalog Number:10-1379Activity:Antimalarial/Autophagy inhibitorChemical Names:7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinolone sulfateMolecular Weight:433.96Molecular Formula:C18H26ClN3O·H2SO4Solubility:Soluble in Water (40 mg/ml)Physical Properties:White solidPurity:98% TLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Hydroxyurea | Anticancer agent
From $54.00CAS:127-07-1Catalog Number:10-3510Activity:Anticancer agentChemical Names:N-Hydroxyurea; HydroxycarbamideMolecular Weight:76.06Molecular Formula:CH4N2O2Solubility:Soluble in water (50 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years as supplied from date of purchase. Solutions in water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Ibandronate | Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drug
From $30.00CAS:138926-19-9Catalog Number:10-4630Activity:Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drugChemical Name:(1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium monohydrateMolecular Weight:359.23Molecular Formula:C9H22NO7P2•Na • H2OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Ibrutinib | BTK inhibitor
From $40.00CAS:936563-96-1Catalog Number:10-4757Alternate Name:PCI-32765Activity:BTK inhibitor/Cancer immunotherapy enhancerChemical Name:1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneMolecular Weight:440.51Molecular Formula:C25H24N6O2Solubility:Soluble in DMSO ( up to at least 25 mg/ml)Physical Properties:White or off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Ibudilast | Neuroinflammation inhibitor
From $40.00CAS:50847-11-5Catalog Number:10-2236Activity:Neuroinflammation inhibitorChemical Name:3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridineAlternate Names:2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridine-3-yl 1-propanone; KC-404; AV411Molecular Weight:230.31Molecular Formula:C14H18N2OSolubility:Soluble in DMSO (up to 25 mg/ml) or Ethanol (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
