Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Isradipine | L-type Ca channel blocker
From $64.00CAS:75695-93-1Catalog Number:10-1202Activity:L-type Ca channel blockerChemical Name:4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl, 1-methylethyl diesterMolecular Weight:371.4Molecular Formula:C19H21N3O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).Physical Properties:Yellow solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchsae as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Itraconazole | Autophagy inducer / Inhibits glioblastoma growth
From $45.00CAS:84625-61-6Catalog Number:10-2033Activity:Autophagy inducer / Inhibits glioblastoma growthAlternate Names:Oriconazole; R51211Molecular Weight:705.63Molecular Formula:C35H36Cl2N8O4Solubility:Soluble in DMSO (up to 1.5 mg/ml with warming)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ivabradine HCl | Heart failure / unstable angina drug
From $60.00CAS:1448849-67-6Catalog Number:10-2694Activity:Heart failure / unstable angina drugChemical Name:3-[3-[[(7S)-3,4-Dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochlorideMolecular Weight:505.05Molecular Formula:C27H36N2O5 • HClSolubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
Ivermectin | Nuclear transport inhibitor
From $30.00CAS:70288-86-7Catalog Number:10-2628Activity:Nuclear transport inhibitorChemical Name:22,23-Dihydroavermectin B1Alternate Name:22,23-Dihydro C076B1; MK-933Molecular Weight:875.09Molecular Formula:C48H74O14 (B1a form)Solubility:Soluble in DMSO (up to 70 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)
Contains up to 10% B1b formStorage Temperature:-20°C (des.)Stability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Ketoconazole | Cytochrome P450 Inhibitor
From $45.00CAS:65277-42-1Catalog Number:10-1015Activity:Cytochrome P450 inhibitorChemical Name:(±)-1-[4-(4-{[-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-oneMolecular Weight:531.43Molecular Formula:C26H28Cl2N4O4Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:Off-white solidPurity:>98% by TLCStorage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
