BiochemicalTargets

Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Griseofulvin | Inhibitor of centrosomal clustering

    CAS:
    126-07-8
    Catalog Number:
    10-2745
    Activity:
    Inhibitor of centrosomal clustering
    Chemical Name:
    Fermentation product from Penicili>ium sp.
    Molecular Weight:
    352.77
    Molecular Formula:
    C17H17ClO6
    Solubility:
    Soluble in DMSO (up to 40 mg/ml), in DMF (up to 50 mg/ml), or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol, or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • GS-441524 | Remdesivir active metabolite

    CAS:
    1191237-69-0
    Catalog Number:
    10-4485
    Activity:
    Remdesivir active metabolite
    Chemical Names:
    (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
    Molecular Weight:
    291.27
    Molecular Formula:
    C12H13N5O4
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
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  • Homoharringtonine | Protein synthesis inhibitor

    CAS:
    26833-87-4
    Catalog Number:
    10-3033
    Activity:
    Protein synthesis inhibitor
    Chemical Names:
    Cephalotaxine 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate
    Alternate Name:
    HHT; NSC141633; Omacetaxine mepesuccinate
    Molecular Weight:
    545.63
    Molecular Formula:
    C29H39NO9
    Solubility:
    Soluble in DMSO (75 mg/ml)
    Physical Properties:
    Pale yellow to off-white solid
    Purity:
    >95% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Hydroxychloroquine sulfate | Autophagy inhibitor

    CAS:
    747-36-4
    Catalog Number:
    10-1379
    Activity:
    Antimalarial/Autophagy inhibitor
    Chemical Names:
    7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinolone sulfate
    Molecular Weight:
    433.96
    Molecular Formula:
    C18H26ClN3O·H2SO4
    Solubility:
    Soluble in Water (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Hydroxyurea | Anticancer agent

    CAS:
    127-07-1
    Catalog Number:
    10-3510
    Activity:
    Anticancer agent
    Chemical Names:
    N-Hydroxyurea; Hydroxycarbamide
    Molecular Weight:
    76.06
    Molecular Formula:
    CH4N2O2
    Solubility:
    Soluble in water (50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied from date of purchase. Solutions in water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $54.00
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  • Ibandronate | Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drug

    CAS:
    138926-19-9
    Catalog Number:
    10-4630
    Activity:
    Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drug
    Chemical Name:
    (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium monohydrate
    Molecular Weight:
    359.23
    Molecular Formula:
    C9H22NO7P2•Na • H2O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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