Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Glyburide | K-ATP channel blocker
From $30.00CAS:10238-21-8Catalog Number:10-1325Activity:K-ATP channel blockerAlternate Names:GlibenclamideChemical Name:5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]suphonyl]phenyl]ethyl]-2-methoxybenzamideMolecular Weight:494.01Molecular Formula:C23H28ClN3O5SSolubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 2 mg/ml with warming).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Griseofulvin | Inhibitor of centrosomal clustering
From $40.00CAS:126-07-8Catalog Number:10-2745Activity:Inhibitor of centrosomal clusteringChemical Name:Fermentation product from Penicili>ium sp.Molecular Weight:352.77Molecular Formula:C17H17ClO6Solubility:Soluble in DMSO (up to 40 mg/ml), in DMF (up to 50 mg/ml), or in Ethanol (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol, or DMF may be stored at -20° for up to 3 months.Shipping Code:RT -
GS-441524 | Remdesivir active metabolite
From $30.00CAS:1191237-69-0Catalog Number:10-4485Activity:Remdesivir active metaboliteChemical Names:(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrileMolecular Weight:291.27Molecular Formula:C12H13N5O4Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Homoharringtonine | Protein synthesis inhibitor
From $60.00CAS:26833-87-4Catalog Number:10-3033Activity:Protein synthesis inhibitorChemical Names:Cephalotaxine 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioateAlternate Name:HHT; NSC141633; Omacetaxine mepesuccinateMolecular Weight:545.63Molecular Formula:C29H39NO9Solubility:Soluble in DMSO (75 mg/ml)Physical Properties:Pale yellow to off-white solidPurity:>95% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Hydroxychloroquine sulfate | Autophagy inhibitor
From $30.00CAS:747-36-4Catalog Number:10-1379Activity:Antimalarial/Autophagy inhibitorChemical Names:7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinolone sulfateMolecular Weight:433.96Molecular Formula:C18H26ClN3O·H2SO4Solubility:Soluble in Water (40 mg/ml)Physical Properties:White solidPurity:98% TLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Hydroxyurea | Anticancer agent
From $54.00CAS:127-07-1Catalog Number:10-3510Activity:Anticancer agentChemical Names:N-Hydroxyurea; HydroxycarbamideMolecular Weight:76.06Molecular Formula:CH4N2O2Solubility:Soluble in water (50 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years as supplied from date of purchase. Solutions in water may be stored at -20°C for up to 3 months.Shipping Code:RT
