Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Ingenol-3-angelate | PKC activator

    CAS:
    75567-37-2
    Catalog Number:
    10-1244
    Activity:
    PKC activator
    Alternate Names:
    PEP-005
    Molecular Weight:
    460.53
    Molecular Formula:
    C25H34O6
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 4 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $110.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Irinotecan HCl | Topoisomerase I inhibitor

    CAS:
    136572-09-3
    Catalog Number:
    10-2146
    Activity:
    Topoisomerase I inhibitor
    Chemical Name:
    (S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4′-bipiperidine]-1′-carboxylate hydrochloride
    Molecular Weight:
    677.2
    Molecular Formula:
    C33H38N4O6 HCl 3H2O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), in Water (up to 4 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Isradipine | L-type Ca channel blocker

    CAS:
    75695-93-1
    Catalog Number:
    10-1202
    Activity:
    L-type Ca channel blocker
    Chemical Name:
    4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl, 1-methylethyl diester
    Molecular Weight:
    371.4
    Molecular Formula:
    C19H21N3O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchsae as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $64.00
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  • Itraconazole | Autophagy inducer / Inhibits glioblastoma growth

    CAS:
    84625-61-6
    Catalog Number:
    10-2033
    Activity:
    Autophagy inducer / Inhibits glioblastoma growth
    Alternate Names:
    Oriconazole; R51211
    Molecular Weight:
    705.63
    Molecular Formula:
    C35H36Cl2N8O4
    Solubility:
    Soluble in DMSO (up to 1.5 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Ivabradine HCl | Heart failure / unstable angina drug

    CAS:
    1448849-67-6
    Catalog Number:
    10-2694
    Activity:
    Heart failure / unstable angina drug
    Chemical Name:
    3-[3-[[(7S)-3,4-Dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride
    Molecular Weight:
    505.05
    Molecular Formula:
    C27H36N2O5 • HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Ivermectin | Nuclear transport inhibitor

    CAS:
    70288-86-7
    Catalog Number:
    10-2628
    Activity:
    Nuclear transport inhibitor
    Chemical Name:
    22,23-Dihydroavermectin B1
    Alternate Name:
    22,23-Dihydro C076B1; MK-933
    Molecular Weight:
    875.09
    Molecular Formula:
    C48H74O14 (B1a form)
    Solubility:
    Soluble in DMSO (up to 70 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Contains up to 10% B1b form
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Plymouth Meeting, PA USA
1-855-FOCUS21

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