BiochemicalTargets

Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Lenvatinib | VEGFR inhibitor

    CAS:
    417716-92-8
    Catalog Number:
    10-3313
    Activity:
    VEGFR inhibitor
    Chemical Name:
    4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
    Alternate Names:
    E7080
    Molecular Weight:
    426.85
    Molecular Formula:
    C21H19ClN4O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Levetiracetam | Anticonvulsant

    CAS:
    102767-28-2
    Catalog Number:
    10-2040
    Activity:
    Anticonvulsant
    Chemical Name:
    2(S)-(2-Oxopyrrolidin-1-yl)butyramide
    Molecular Weight:
    170.21
    Molecular Formula:
    C29H14N2O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Lomerizine | Calcium Channel Blocker

    CAS:
    101477-54-7
    Catalog Number:
    10-4336
    Activity:
    Calcium Channel Blocker
    Chemical Name:
    1-[Bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride
    Alternate Names:
    KB-2796
    Molecular Weight:
    541.46
    Molecular Formula:
    C27H30F2N2O3•2HCl
    Solubility:
    Soluble in DMSO (up to 45 mg/ml) and Ethanol (30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • Lomitapide | Microsomal triglyceride transfer protein inhibitor

    CAS:
    182431-12-5
    Catalog Number:
    10-4664
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  • Losartan potassium | Angiotensin AT1 antagonist

    CAS:
    124750-99-8
    Catalog Number:
    10-2294
    Activity:
    Angiotensin AT1 antagonist
    Alternate Names:
    DUP-753
    Chemical Name:
    2-Butyl-4-chloro-1-{[2′-(1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol, potassium salt
    Molecular Weight:
    461.01
    Molecular Formula:
    C22H22ClKN6O
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $40.00
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  • Lovastatin | HMG-CoA reductase inhibitor

    CAS:
    75330-75-5
    Catalog Number:
    10-1222
    Activity:
    HMG-CoA reductase inhibitor
    Alternate Names:
    Mevinolin
    Chemical Name:
    2-Methyl-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acid
    Molecular Weight:
    404.55
    Molecular Formula:
    C24H36O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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