Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Ivermectin | Nuclear transport inhibitor

    CAS:
    70288-86-7
    Catalog Number:
    10-2628
    Activity:
    Nuclear transport inhibitor
    Chemical Name:
    22,23-Dihydroavermectin B1
    Alternate Name:
    22,23-Dihydro C076B1; MK-933
    Molecular Weight:
    875.09
    Molecular Formula:
    C48H74O14 (B1a form)
    Solubility:
    Soluble in DMSO (up to 70 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Contains up to 10% B1b form
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Ixazomib | Proteasome inhibitor

    CAS:
    1072833-77-2
    Catalog Number:
    10-5185
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  • Ketanserin tartrate | Serotonin 5-HT2A antagonist

    CAS:
    83846-83-7
    Catalog Number:
    10-2490
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  • Ketoconazole | Cytochrome P450 Inhibitor

    CAS:
    65277-42-1
    Catalog Number:
    10-1015
    Activity:
    Cytochrome P450 inhibitor
    Chemical Name:
    (±)-1-[4-(4-{[-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
    Molecular Weight:
    531.43
    Molecular Formula:
    C26H28Cl2N4O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Lamivudine | Reverse transcriptase inhibitor

    CAS:
    134678-17-4
    Catalog Number:
    10-2028
    Activity:
    Reverse transcriptase inhibitor
    Chemical Names:
    4-Amino-1-[(2R,5S)-2-(hydroxymethyl)1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
    Alternate Name:
    (-)-BCH-189; 3TC
    Molecular Weight:
    229.25
    Molecular Formula:
    C8H11N3O3S
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Lapatinib | EGFR and HER2 inhibitor

    CAS:
    231277-92-2
    Catalog Number:
    10-2147
    Activity:
    EGFR and HER2 inhibitor
    Chemical Name:
    N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine
    Alternate Names:
    GW-572016
    Molecular Weight:
    581.06
    Molecular Formula:
    C29H26ClFN4O4S
    Solubility:
    Soluble in DMSO (up to 200 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $55.00
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