Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Lovastatin | HMG-CoA reductase inhibitor
From $50.00CAS:75330-75-5Catalog Number:10-1222Activity:HMG-CoA reductase inhibitorAlternate Names:MevinolinChemical Name:2-Methyl-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acidMolecular Weight:404.55Molecular Formula:C24H36O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Manidipine dihydrochloride | Calcium channel blocker
From $30.00CAS:89226-75-5Catalog Number:10-2045Activity:Calcium channel blockerChemical Names:5-O-[2-(4-Benzhydrylpiperazin-1-yl)ethyl] 3-O-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochlorideAlternate Name:CV-4093Molecular Weight:683.63Molecular Formula:C35H38N4O6·2HClSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Maraviroc | CCR5 Antagonist
From $50.00CAS:376348-65-1Catalog Number:10-4260Activity:CCR5 AntagonistChemical Name:4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamideAlternate Name:UK-427,857Molecular Weight:513.68Molecular Formula:C29H41F2N5OSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:>98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Memantine HCl | NMDA antagonist / Anti-Alzheimer’s
From $50.00CAS:41100-52-1Catalog Number:10-2346Activity:NMDA antagonist / Anti-Alzheimer’sChemical Name:3,5-Dimethyl-tricyclo[3.3.1.13,7]decam-1-amine HClAlternate Names:3,5-Dimethyl-tricyclo[3.3.1.13,7]decam-1-amine HClMolecular Weight:215.76Molecular Formula:C12H21N • HClSolubility:Soluble in Water (up to 20 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.Shipping Code:RT -
Metergoline | Serotonin 5HT1,2,7 antagonist
From $35.00CAS:17692-51-2Catalog Number:10-3058Activity:Serotonin 5HT1,2,7 antagonistChemical Names:[(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl esterMolecular Weight:403.52Molecular Formula:C25H29N3O2Solubility:Soluble in DMSO (40 mg/ml) or ethanol (4 mg/mL)Physical Properties:White solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethaqnol may be stored at -20°C for up to 2 month.Shipping Code:RT -
Metformin HCl | Anti-diabetic agent
From $30.00CAS:1115-70-4Catalog Number:10-2469Activity:Anti-diabetic agentChemical Name:1,1-Dimethylbiguanide hydrochlorideMolecular Weight:165.63Molecular Formula:C4H11N5 HClSolubility:Soluble in DMSO (up to 8 mg/ml) or in Water (up to 16 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.Shipping Code:RT
