Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Larotrectinib | TRK inhibitor

    CAS:
    1223403-58-4
    Catalog Number:
    10-4832
    Activity:
    Potent and selective panTRK inhibitor
    Chemical Name:
    (3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)pyrrolidine-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide
    Alternate Name:
    LOXO-101; ARRY-470
    Molecular Weight:
    428.44
    Molecular Formula:
    C21H22F2N5O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • Leflunomide | Immunosuppressant

    CAS:
    75706-12-6
    Catalog Number:
    10-2369
    Activity:
    Immunosuppressant
    Alternate Names:
    RS-34821
    Chemical Name:
    5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
    Molecular Weight:
    270.21
    Molecular Formula:
    C12H9F3N2O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • Lenalidomide | Immunomodulator

    CAS:
    191732-72-6
    Catalog Number:
    10-2148
    Activity:
    Immunomodulator
    Chemical Name:
    (R,S)-3-(4-Amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione
    Molecular Weight:
    259.26
    Molecular Formula:
    C13H13N3O3
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Lenvatinib | VEGFR inhibitor

    CAS:
    417716-92-8
    Catalog Number:
    10-3313
    Activity:
    VEGFR inhibitor
    Chemical Name:
    4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
    Alternate Names:
    E7080
    Molecular Weight:
    426.85
    Molecular Formula:
    C21H19ClN4O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Levetiracetam | Anticonvulsant

    CAS:
    102767-28-2
    Catalog Number:
    10-2040
    Activity:
    Anticonvulsant
    Chemical Name:
    2(S)-(2-Oxopyrrolidin-1-yl)butyramide
    Molecular Weight:
    170.21
    Molecular Formula:
    C29H14N2O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Lomerizine | Calcium Channel Blocker

    CAS:
    101477-54-7
    Catalog Number:
    10-4336
    Activity:
    Calcium Channel Blocker
    Chemical Name:
    1-[Bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride
    Alternate Names:
    KB-2796
    Molecular Weight:
    541.46
    Molecular Formula:
    C27H30F2N2O3•2HCl
    Solubility:
    Soluble in DMSO (up to 45 mg/ml) and Ethanol (30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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