Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Lomitapide chemical structure Focus Biomolecules

    Lomitapide | Microsomal triglyceride transfer protein inhibitor

    CAS:
    182431-12-5
    Catalog Number:
    10-4664
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  • Lopinavir chemical structure

    Lopinavir | HIV-1 protease inhibitor

    CAS:
    192725-17-0
    Catalog Number:
    10-5063
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  • Losartan potassium | Angiotensin AT1 antagonist

    CAS:
    124750-99-8
    Catalog Number:
    10-2294
    Activity:
    Angiotensin AT1 antagonist
    Alternate Names:
    DUP-753
    Chemical Name:
    2-Butyl-4-chloro-1-{[2′-(1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol, potassium salt
    Molecular Weight:
    461.01
    Molecular Formula:
    C22H22ClKN6O
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $40.00
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  • Lovastatin | HMG-CoA reductase inhibitor

    CAS:
    75330-75-5
    Catalog Number:
    10-1222
    Activity:
    HMG-CoA reductase inhibitor
    Alternate Names:
    Mevinolin
    Chemical Name:
    2-Methyl-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acid
    Molecular Weight:
    404.55
    Molecular Formula:
    C24H36O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • Manidipine dihydrochloride | Calcium channel blocker

    CAS:
    89226-75-5
    Catalog Number:
    10-2045
    Activity:
    Calcium channel blocker
    Chemical Names:
    5-O-[2-(4-Benzhydrylpiperazin-1-yl)ethyl] 3-O-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride
    Alternate Name:
    CV-4093
    Molecular Weight:
    683.63
    Molecular Formula:
    C35H38N4O6·2HCl
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Maraviroc | CCR5 Antagonist

    CAS:
    376348-65-1
    Catalog Number:
    10-4260
    Activity:
    CCR5 Antagonist
    Chemical Name:
    4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide
    Alternate Name:
    UK-427,857
    Molecular Weight:
    513.68
    Molecular Formula:
    C29H41F2N5O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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