Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Minocycline HCl | Neuroprotective/anti-inflammatory
From $60.00CAS:13614-98-7Catalog Number:10-2568Activity:Neuroprotective; antiapoptoticChemical Name:[4S-(4_,4a_,5a_,12a_)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide hydrochlorideMolecular Weight:493.95Molecular Formula:C23H27N3O7 HClSolubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
Minoxidil | KATP channel opener
From $50.00CAS:38304-91-5Catalog Number:10-1214Activity:KATP channel openerChemical Name:6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxideMolecular Weight:209.25Molecular Formula:C9H15N5OSolubility:Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Mirabegron | beta-3 Adrenergic agonist
CAS:223673-61-8Catalog Number:10-4228 -
Mitapivat | Pyruvate kinase activator
From $80.00CAS:1260075-17-9Catalog Number:10-4479Activity:Pyruvate kinase activatorChemical Names:N-[4-[4-(Cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamideAlternate Name:AG-348Molecular Weight:450.56Molecular Formula:C24H26N4O3SSolubility:Soluble in DMSO (>50 mg/ml)Physical Properties:Beige solidPurity:99% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Mitomycin C | DNA crosslinking and damaging agent
From $55.00CAS:50-07-7Catalog Number:10-1170Activity:DNA crosslinking and damaging agentChemical Name:Natural fermentation product from Streptomyces sp.Molecular Weight:334.33Molecular Formula:C15H18N4O5Solubility:Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).Physical Properties:Blue-violet solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.Shipping Code:RT -
Montelukast sodium | Leukotriene antagonist and GPR17 antagonist
From $60.00CAS:151767-02-1Catalog Number:10-2597Activity:Leukotriene antagonist and GRP17 antagonistChemical Name:2-[1-[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate, sodium saltAlternate Names:MK-0476Molecular Weight:608.17Molecular Formula:C35H35ClNO3SSolubility:Soluble in DMSO (up to 60 mg/ml), in Water (up to 30 mg/ml) , or in Ethanol (up to 60 mg/ml)Physical Properties:SolidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water, or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
