Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Naloxone HCl | Opioid receptor antagonist
From $95.00CAS:357-08-4Catalog Number:10-2442Activity:Opiod receptor antagonistChemical Name:(5α)-4,5-Epoxy-3,14-dihydro-17-(2-propenyl)morphinan-6-one hydrochlorideMolecular Weight:363.84Molecular Formula:C19H21NO4 &bul; HClSolubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 25 mg/ml).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.Shipping Code:RT -
Nelfinavir mesylate | HIV protease inhibitor / Anticancer activity
From $60.00CAS:159989-65-8Catalog Number:10-3050Activity:HIV protease inhibtior / Anticancer activityChemical Name:(3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonateAlternate Name:AG-1343Molecular Weight:663.88Molecular Formula:C32H45N3O4S • CH3SO3HSolubility:Soluble in DMSO (up to 70 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor
From $30.00CAS:54527-84-3Catalog Number:10-1201Activity:L-type Ca channel blocker / MDR inhibitorChemical Name:1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid methyl ester hydrochlorideMolecular Weight:515.99Molecular Formula:C26H29N3O6·HClSolubility:Soluble in Ethanol (up to 20 mg/ml) or in Water (up to 5 mg/ml).Physical Properties:Pale-yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Niclosamide | STAT3 signaling inhibitor
From $28.00CAS:50-65-7Catalog Number:10-2474Activity:STAT3 signaling inhibitorChemical Name:5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamideMolecular Weight:327.13Molecular Formula:C13H8Cl2N2O4Solubility:Soluble in DMSO (up to 3 mg/ml), or in Ethanol (up to 6 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Nifedipine | L-type Ca channel blocker
From $40.00CAS:21829-25-4Catalog Number:10-1116Activity:L-type Ca channel blockerChemical Name:2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl esterMolecular Weight:346.34Molecular Formula:C17H18N2O6Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be used within one working day.Shipping Code:RT -
Nilotinib | BCR-ABL inhibitor
From $30.00CAS:641571-10-0Catalog Number:10-2152Activity:BCR-ABL inhibitorChemical Name:4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamideAlternate Names:AMN107Molecular Weight:529.52Molecular Formula:C28H22F3N7OSolubility:Soluble in DMSO (up to 50 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
