Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Obeticholic Acid | FXR agonist
From $50.00CAS:459789-99-2Catalog Number:10-2838Activity:FXR agonistChemical Name:3α-7α-dihydroxy-6α-ethyl-5ß-cholan-24-oic acidAlternate Names:6-Ethylchenodeoxycholic acid; 6-ECDCAMolecular Weight:420.63Molecular Formula:C26H44O4Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Olaparib | PARP1 inhibitor
From $45.00CAS:763113-22-0Catalog Number:10-2154Activity:PARP1 inhibitorChemical Name:4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-oneAlternate Names:AZD-2281; KU-59436Molecular Weight:434.47Molecular Formula:C24H23FN4O3Solubility:Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Omeprazole | Proton pump inhibitor / Antiviral
From $38.00CAS:73590-58-6Catalog Number:10-2822Activity:Proton pump inhibitor / AntiviralChemical Name:5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazoleMolecular Weight:345.42Molecular Formula:C17H19N3O3SSolubility:Soluble in DMSO (up to 35 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 months.Shipping Code:RT -
Orlistat | DAG Lipase-α inhibitor
From $30.00CAS:96829-58-2Catalog Number:10-2448Activity:DAG Lipase-α inhibitorAlternate Names:Ro18-0647, (-)-TetrahydrolipstatinChemical Name:N-Formyl-L-leucine (1S)-10[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl esterMolecular Weight:495.75Molecular Formula:C29H53NO5Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.Shipping Code:RT -
Oseltamivir Phosphate | Neuraminidase inhibitor / Antiviral
From $30.00CAS:204255-11-9Catalog Number:10-4483Activity:Neuraminidase inhibitor / AntiviralChemical Name:Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate phosphoric acid saltAlternate Name:GS4104; TamifluMolecular Weight:410.40Molecular Formula:C16H28N2O4•H3PO4Solubility:Soluble in DMSO (up to 40 mg/ml) or in Water (up to at least 40 mg/ml).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Osimertinib | Mutant EGFR kinase inhibitor
CAS:1421373-65-0Catalog Number:10-5036
