Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Nifedipine | L-type Ca channel blocker
From $40.00CAS:21829-25-4Catalog Number:10-1116Activity:L-type Ca channel blockerChemical Name:2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl esterMolecular Weight:346.34Molecular Formula:C17H18N2O6Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be used within one working day.Shipping Code:RT -
Nilotinib | BCR-ABL inhibitor
From $30.00CAS:641571-10-0Catalog Number:10-2152Activity:BCR-ABL inhibitorChemical Name:4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamideAlternate Names:AMN107Molecular Weight:529.52Molecular Formula:C28H22F3N7OSolubility:Soluble in DMSO (up to 50 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Nilvadipine | Syk inhibitor/Calcium channel blocker
From $70.00CAS:75530-68-6Catalog Number:10-3035Activity:Syk inhibitor and Calcium channel blockerChemical Name:2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-(1-methylethyl) esterAlternate Names:FR34235Molecular Weight:385.38Molecular Formula:C19H19N3O6Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Nimodipine | L-type calcium channel blocker
From $50.00CAS:66085-59-4Catalog Number:10-1321Activity:L-type calcium channel blockerChemical Name:1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methyloxyethyl 1-methylethyl esterAlternate Names:BAY-e 9736Molecular Weight:418.44Molecular Formula:C21H26N2O7Solubility:Soluble in DMSO (up to 40 mg/ml)Physical Properties:Pale-yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Nitazoxanide | Wnt signaling inhibitor
From $40.00CAS:55981-09-4Catalog Number:10-4633Activity:Wnt signaling inhibitorChemical Names:O-[N-(5-Nitrothiazol-2-yl)carbamoyl]phenyl acetate; NTZMolecular Weight:307.28Molecular Formula:C12H9N3O5SSolubility:Soluble in DMSO (>50 mg/ml)Physical Properties:Off-white solidPurity:99% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
