Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Pemetrexed 2Na | Multitargeted antifolate

    CAS:
    357166-29-1
    Catalog Number:
    10-2162
    Activity:
    Multi-targeted antifolate
    Chemical Name:
    N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium salt
    Molecular Weight:
    597.49
    Molecular Formula:
    C20H19N5O6 • 2Na • 7H2O
    Solubility:
    Soluble in Water (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC and HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.
    Shipping Code:
    RT
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  • Perphenazine | Antipsychotic agent

    CAS:
    58-39-9
    Catalog Number:
    10-4709
    Activity:
    Typical antipsychotic
    Chemical Name:
    2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
    Molecular Weight:
    403.98
    Molecular Formula:
    C21H26ClN3OS
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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  • Phenoxybenzamine HCl | Calmodulin antagonist

    CAS:
    63-92-3
    Catalog Number:
    10-1237
    Activity:
    Calmodulin antagonist
    Chemical Name:
    N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride
    Molecular Weight:
    340.29
    Molecular Formula:
    C18H22ClNO HCl
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 15 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Phenylbutyrate Na | HDAC inhibitor

    CAS:
    1716-12-7
    Catalog Number:
    10-1118
    Activity:
    HDAC inhibitor
    Alternate Names:
    4-PB, PBNa
    Chemical Name:
    4-Phenylbutyric acid sodium salt
    Molecular Weight:
    186.18
    Molecular Formula:
    C10H11NaO2
    Solubility:
    Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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  • Pimaricin (Natamycin) | Antifungal Polyene macrolide

    CAS:
    7681-93-8
    Catalog Number:
    10-2742
    Activity:
    Antifungal Polyene macrolide
    Alternate Names:
    Natamycin
    Chemical Name:
    Fermentation product from Streptomyces chattanoogensis
    Molecular Weight:
    665.74
    Molecular Formula:
    C3347NO13
    Solubility:
    Soluble in DMSO (up to 7 mg/ml). Only slightly soluble in Ethanol (less than 1 mg/ml).
    Physical Properties:
    Cream colored solid
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $48.00
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  • Pioglitazone HCl | PPAR gamma agonist

    CAS:
    112529-15-4
    Catalog Number:
    10-1010
    Activity:
    PPARγ agonist
    Chemical Name:
    5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride
    Molecular Weight:
    392.90
    Molecular Formula:
    C19H20N2O3S·HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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