Kinases Archives

Afatinib | EGFR and HER2 inhibitor

CAS:

850140-72-6

Catalog Number:

10-4510

Activity:

EGFR and HER2 inhibitor

Chemical Name:

N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide

Alternate Names:

BIBW2992

Molecular Weight:

485.94

Molecular Formula:

C₂₄H₂₅ClFN₅O₃

Solubility:

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Physical Properties:

Pale yellow solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $45.00
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AG 1478 | EGFR kinase inhibitor

CAS:

175178-82-2

Catalog Number:

10-2117

Activity:

EGFR kinase inhibitor

Chemical Name:

N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine, free base

Molecular Weight:

315.76

Molecular Formula:

C₁₆H₁₄ClN₃O₂

Solubility:

Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming).

Physical Properties:

Off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page
AG-1296 | PDGFR kinase inhibitor

CAS:

146535-11-7

Catalog Number:

10-1087

Activity:

PDGFR kinase inhibitor

Chemical Name:

6,7-Dimethoxy-3-phenylquinoxaline

Molecular Weight:

266.3

Molecular Formula:

C₁₆H₁₄N₂O₂

Solubility:

Soluble in DMSO.

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $60.00
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AG-1517 HCl | EGFR kinase inhibitor

CAS:

153436-54-5

Catalog Number:

10-1377

Activity:

EGFR kinase inhibitor

Alternate Names:

PD153,053; SU-5271; Z-252868

Chemical Name:

4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride

Molecular Weight:

360.21

Molecular Formula:

C₁₆H₁₄BrN₃O₂

Solubility:

Soluble in DMSO (up to 5 mg/ml).

Physical Properties:

White or off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

RT

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $70.00
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AG-490 | JAK2 inhibitor

CAS:

133550-30-8

Catalog Number:

10-1091

Activity:

JAK2 inhibitor

Chemical Name:

(E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide

Molecular Weight:

294.31

Molecular Formula:

C₁₇H₁₄N₂O₃

Solubility:

Soluble in DMSO (up to 25 mg/ml), in DMF (up to 40 mg/ml), or in Ethanol (up to 10 mg/ml).

Physical Properties:

Tan solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page

Kinases

Afatinib | EGFR and HER2 inhibitor

AG 1478 | EGFR kinase inhibitor

AG-1296 | PDGFR kinase inhibitor

AG-1517 HCl | EGFR kinase inhibitor

AG-490 | JAK2 inhibitor

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

Afatinib | EGFR and HER2 inhibitor

AG 1478 | EGFR kinase inhibitor

AG-1296 | PDGFR kinase inhibitor

AG-1517 HCl | EGFR kinase inhibitor

AG-490 | JAK2 inhibitor

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21