Immuno-oncology
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Lenalidomide | Immunomodulator
From $75.00CAS:191732-72-6Catalog Number:10-2148Activity:ImmunomodulatorChemical Name:(R,S)-3-(4-Amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dioneMolecular Weight:259.26Molecular Formula:C13H13N3O3Solubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Loxoribine | TLR7 agonist
From $30.00CAS:121288-39-9Catalog Number:10-3780Activity:TLR7 agonistChemical Name:7-Allyl-7,8-dihydro-8-oxoguanosineAlternate Name:RWJ-21757Molecular Weight:339.30Molecular Formula:C13H17N5O6Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:White solidPurity:96% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Luminespib | HSP90 inhibitor
From $45.00CAS:747412-49-3Catalog Number:10-4672Activity:HSP90 inhibitorChemical Names:5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamideAlternate Name:NVP-AUY922; VER-52296Molecular Weight:465.54Molecular Formula:C26H31N3O5Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:99% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Maraviroc | CCR5 Antagonist
From $50.00CAS:376348-65-1Catalog Number:10-4260Activity:CCR5 AntagonistChemical Name:4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamideAlternate Name:UK-427,857Molecular Weight:513.68Molecular Formula:C29H41F2N5OSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:>98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Motolimod | TLR8 agonist
From $80.00CAS:926927-61-9Catalog Number:10-4920Activity:TLR8 agonist/Cancer immunotherapy enhancerAlternate Name:VTX-2337Chemical Name:2-Amino-N,N-dipropyl-8-[4-(pyrrolidine-1-carbonyl)phenyl]-3H-1-benzapine-4-carboxamideMolecular Weight:458.61Molecular Formula:C28H34N4O2Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Off-white or pale yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
