CELLULAR METABOLISM

Daily function of cells involves many biochemical pathways that continuously monitor and balance energy homeostasis. Disruption of cellular metabolism can lead to diseases that affect most systems in the body. A hallmark of cancer, for example, is a restructuring of normal cellular metabolism to meet the energetic and stress demands inherent in rapid cell growth. Diseases that involve inborn errors of metabolism (IEM’s) include phenylketonuria, Niemann-Pick disease, and glycogen storage diseases.

Complex Carbohydrates

  • Migalastat HCl | Galactosidase inhibitor/Pharmacological chaperone
    CAS:
    75172-81-5
    Catalog Number:
    10-2632
  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • Tunicamycin | ER stress inducer
    CAS:
    11089-65-9
    Catalog Number:
    10-2111
    Activity:
    ER stress inducer
    Molecular Weight:
    840.0 (Avg)
    Molecular Formula:
    C38H62N4O16 (tun. B)
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Kifunensine | Mannosidase inhibitor
    CAS:
    109944-15-2
    Catalog Number:
    10-2860
    Activity:
    Mannosidase inhibitor
    Chemical Name:
    (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione
    Alternate Names:
    FR-900494
    Molecular Weight:
    232.19
    Molecular Formula:
    C8H12N2O6
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Swainsonine | Glycosidase inhibitor
    CAS:
    72741-87-8
    Catalog Number:
    10-2674
    Activity:
    Glycosidase inhibitor
    Chemical Name:
    (1S,2R,8R,8aR)-octahydro-1,2,8-indolizinetriol
    Molecular Formula:
    C8H15NO3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml), in Ethanol (up to 10 mg/ml) or in Water (up to 8 mg/ml)
    Physical Properties:
    White or off-white solid solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Complex Carbohydrates Products

Glucose

  • Mito-lonidamine | Mitochondria-targeted antiglycolytic agent
    CAS:
    2361564-49-8
    Catalog Number:
    10-5492
  • CBR-470-1 | NRF2 signaling activator
    CAS:
    2416095-06-0
    Catalog Number:
    10-4680
  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • NG52 | Phosphoglycerate kinase 1 inhibitor
    CAS:
    212779-48-1
    Catalog Number:
    10-4681
    Activity:
    Phosphoglycerate kinase 1 inhibitor
    Chemical Names:
    2-[[6-(3-Chloroanilino)-9-propan-2-ylpurin-2-yl]amino]ethanol
    Molecular Weight:
    346.82
    Molecular Formula:
    C16H19ClN6O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Mitapivat | Pyruvate kinase activator
    CAS:
    1260075-17-9
    Catalog Number:
    10-4479
    Activity:
    Pyruvate kinase activator
    Chemical Names:
    N-[4-[4-(Cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide
    Alternate Name:
    AG-348
    Molecular Weight:
    450.56
    Molecular Formula:
    C24H26N4O3S
    Solubility:
    Soluble in DMSO (>50 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Glucose Products

Glutamine

  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • Gilteritinib | FLT3 Inhibitor
    CAS:
    1254053-43-4
    Catalog Number:
    10-4170
    Activity:
    FLT3 inhibitor
    Chemical Names:
    6-Ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide; ASP2215
    Molecular Weight:
    552.72
    Molecular Formula:
    C29H44N8O3
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    Off-white to pale pink solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • GAC Inhibitor 968 | Glutaminase C inhibitor
    CAS:
    311795-38-7
    Catalog Number:
    10-1538
    Activity:
    Glutaminase C inhibitor
    Chemical Names:

    5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]-phenanthridin-4(1H)-one

    Molecular Weight:
    475.42
    Molecular Formula:
    C27H27BrN2O
    Solubility:
    Soluble in DMSO (up to 11 mg/ml) or in Ethanol (up to 1 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98%  TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • BPTES | Glutaminase GLS1 inhibitor
    CAS:
    314045-39-1
    Catalog Number:
    10-5414
    Activity:
    Glutaminase GLS1 inhibitor
    Chemical Name:
    N,N’-[Thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bisbenzeneacetamide
    Molecular Weight:
    524.68
    Molecular Formula:
    C24H24N6O2S3
    Solubility:
    Soluble in DMSO (10 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    98% by TLC NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • R162 | Glutamate dehydrogenase 1 inhibitor
    CAS:
    64302-87-0
    Catalog Number:
    10-4603
    Activity:
    Glutamate Dehydrogenase 1 inhibitor
    Chemical Name:
    1-Hydroxy-2-(2-propen-1-yl)-9,10-anthracenedione
    Alternate Names:
    Purpurin analog
    Molecular Weight:
    264.28
    Molecular Formula:
    C17H12O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Glutamine Products

Glutathione

  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • DT-109 | Induces glutathione biosynthesis
    CAS:
    14857-82-0
    Catalog Number:
    10-5732
    Activity:
    Induces glutathione biosynthesis
    Chemical Names:
    Glycyl-glycyl-L-leucine; Gly-Gly-Leu-OH
    Molecular Weight:
    245.28
    Molecular Formula:
    C10H19N3O4
    Solubility:
    Soluble in DMSO (25 mg/ml with warming); Water (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • RSL3 | GPX4 inhibitor/Ferroptosis inducer
    CAS:
    1219810-16-8
    Catalog Number:
    10-3417
    Activity:
    GPX4 inhibitor/Ferroptosis inducer
    Chemical Names:
    (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
    Alternate Name:
    1S,3R-RSL3
    Molecular Weight:
    440.88
    Molecular Formula:
    C23H21ClN2O5
    Solubility:
    Soluble in DMSO (45 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • 2-AAPA | Glutathione/thioredoxin reductase inhibitor
    CAS:
    1133387-90-2
    Catalog Number:
    10-3238
    Activity:
    Glutathione/thioredoxin reductase inhibitor
    Chemical Names:
    R,R′-2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylthiocarbonylamino)-phenylthiocarbamoylsulfanyl]propionic acid, hydrate
    Molecular Weight:
    518.65
    Molecular Formula:
    C18H22N4O6S4
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    95% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month1.
    Shipping Code:
    RT
  • L-Buthionine Sulfoximine | GCL inhibitor
    CAS:
    83730-53-4
    Catalog Number:
    10-4572
    Activity:
    GCL inhibitor
    Chemical Name:
    2(S)-Amino-4-(S-butylsulfonimidoyl)butanoic acid
    Molecular Weight:
    222.31
    Molecular Formula:
    C8H18N2O3S
    Solubility:
    Soluble in Water (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily.
    Shipping Code:
    RT
View All Glutathione Products

Kinases

  • UNC7467 | IP6K inhibitor
    CAS:
    2922283-43-8
    Catalog Number:
    10-4080
  • CBR-470-1 | NRF2 signaling activator
    CAS:
    2416095-06-0
    Catalog Number:
    10-4680
  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • NG52 | Phosphoglycerate kinase 1 inhibitor
    CAS:
    212779-48-1
    Catalog Number:
    10-4681
    Activity:
    Phosphoglycerate kinase 1 inhibitor
    Chemical Names:
    2-[[6-(3-Chloroanilino)-9-propan-2-ylpurin-2-yl]amino]ethanol
    Molecular Weight:
    346.82
    Molecular Formula:
    C16H19ClN6O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • IM156 | AMPK activator/Mitochondrial protein complex I inhibitor
    CAS:
    1422365-93-2
    Catalog Number:
    10-4657
    Activity:
    AMPK activator/Mitochondrial complex I inhibitor
    Chemical Names:
    N’-[N’-[4-(Trifluoromethoxy)phenyl]carbamimidoyl]pyrrolidine-1-carboxamidine
    Alternate Name:
    HL156A; Lixumistat
    Molecular Weight:
    315.30
    Molecular Formula:
    C13H16F3N5O
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
View All Kinases Products

Lipid Metabolism

  • S07-2010 | pan-AKR1C inhibitor
    CAS:
    1223194-71-5
    Catalog Number:
    10-4148
  • Bempedoic acid | ATP citrate lyase inhibitor
    CAS:
    738606-46-7
    Catalog Number:
    10-4114
  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • VY-3-135 | Acetyl-CoA synthetase 2 inhibitor
    CAS:
    1824637-41-3
    Catalog Number:
    10-4096
    Activity:
    ACSS2 inhibitor
    Chemical Names:
    3-Ethyl-2-[hydroxy(diphenyl)methyl]-N-[(2R)-2-hydroxypropyl]benzimidazole-5-carboxamide
    Molecular Weight:
    429.52
    Molecular Formula:
    C26H27N3O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Firsocostat | Allosteric acetyl-CoA carboxylase inhibitor
    CAS:
    1434635-54-7
    Catalog Number:
    10-4699
    Activity:
    Allosteric ACC inhibitor
    Chemical Names:
    2-[1-[(2R)-2-(2-Methoxyphenyl)-2-9oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxothieno[2,3-d]pyrimidin-3-yl]-2-methylpropanoic acid
    Alternate Name:
    ND-630; NDI-010976; GS-0976
    Molecular Weight:
    569.63
    Molecular Formula:
    C28H31N3O8S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Lipid Metabolism Products

Mitochondrial

  • Vorasidenib | Isocitrate dehydrogenase 1/2 inhibitor
    CAS:
    1644545-52-7
    Catalog Number:
    10-4659
  • BML-260 | JSP-1 phosphatase inhibitor
    CAS:
    101439-76-3
    Catalog Number:
    10-5153
    Activity:
    JSP-1 phosphatase inhibitor
    Chemical Names:
    (Z)-4-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid
    Molecular Weight:
    341.40
    Molecular Formula:
    C17H11NO3S2
    Solubility:
    Soluble in DMSO (45 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • PF-4708671 dihydrochloride | S6K1 inhibitor
    CAS:
    125517-76-0 (free base)
    Catalog Number:
    10-4856
    Activity:
    S6K1 inhibitor
    Chemical Names:
    2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzimidazole dihydrochloride
    Molecular Weight:
    463.33
    Molecular Formula:
    C19H21F3N6·2HCl
    Solubility:
    Soluble in DMSO (at least 35 mg/ml); Water (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month. Hygroscopic solid – protect from moisture.
    Shipping Code:
    RT
  • Ascochlorin | Mitochondrial cytochrome bc1 complex inhibitor
    CAS:
    26166-39-2
    Catalog Number:
    10-5296
  • Visomitin | Mitochondria-targeted antioxidant
    CAS:
    934826-68-3
    Catalog Number:
    10-3913
View All Mitochondrial Products

NAD

  • STF-118804 | NAMPT inhibitor
    CAS:
    894187-61-2
    Catalog Number:
    10-5640
  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • P7C3-A20 | NAMPT activator/Proneurogenic agent
    CAS:
    1235481-90-9
    Catalog Number:
    10-3414
    Activity:
    NAMPT activator/proneurogenic agent
    Chemical Names:
    3,6-Dibromo-ß-fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine
    Molecular Weight:
    506.21
    Molecular Formula:
    C22H19Br2FN2O
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • GKT-137831 | NADPH oxidase NOX1/4 inhibitor
    CAS:
    1218942-37-0
    Catalog Number:
    10-5044
    Activity:
    NADPH oxidase NOX1/4 inhibitor
    Chemical Name:
    2-(2-Chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
    Alternate Name:
    Setanaxib
    Molecular Weight:
    394.85
    Molecular Formula:
    C21H19ClN4O2
    Solubility:
    Soluble in DMSO (up to 65 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • CHS-828 | NAMPT inhibitor
    CAS:
    200484-11-3
    Catalog Number:
    10-1390
    Activity:
    NAMPT inhibitor
    Chemical Name:
    N-[6-(4-Chlorophenoxy)hexyl]-N’-cyano-N”-4-pyridinyl-guanidine
    Alternate Names:
    GMX-1778
    Molecular Weight:
    371.86
    Molecular Formula:
    C19H22ClN5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All NAD Products

Nucleotide

  • Raltitrexed | Thymidylate synthase inhibitor
    CAS:
    112887-68-0
    Catalog Number:
    10-4052
  • Methylbenzoprim | Dual thymidylate synthase/dihydrofolate reductase inhibitor
    CAS:
    118344-71-1
    Catalog Number:
    10-4892
  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • DS18561882 | MTHFD2 inhibitor
    CAS:
    2227149-22-4
    Catalog Number:
    10-4188
    Activity:
    MTHFD2 inhibitor
    Chemical Names:
    N-[4-[8-[(3S)-3,4-Dimethylpiperazin-1-yl]-7-methyl-5-oxo-2,4-dihydro-1H-chromeno[3,4-c]pyridine-3-carbonyl]-2-(trifluoromethoxy)phenyl]methanesulfonamide
    Alternate Name:
    DS18
    Molecular Weight:
    608.63
    Molecular Formula:
    C28H31F3N4O6S
    Solubility:
    Soluble in DMSO (at least 40 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • 6-Mercaptopurine | Purine antimetabolite and immunomodulator
    CAS:
    6112-76-1
    Catalog Number:
    10-4698
    Activity:
    Purine antimetabolite and immunomodulator
    Chemical Names:
    3,7-Dihydropurine-6-thione monohydrate
    Alternate Name:
    6-MP
    Molecular Weight:
    170.19
    Molecular Formula:
    C5H4N4S·H2O
    Solubility:
    Soluble in DMSO (>50 mg/ml); ethanol (5 mg/ml with warming)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Nucleotide Products

Other Cellular Metabolism

View All Other Cellular Metabolism Products

Polyamine

  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • Mitoguazone 2HCl | Polyamine biosynthesis inhibitor / SAM decarboxylase inhibitor
    CAS:
    7059-23-6
    Catalog Number:
    10-4552
    Activity:
    Polyamine biosynthesis inhibitor / SAM decarboxylase inhibitor
    Alternate Names:
    MGBG
    Chemical Name:
    Methylglyoxal bis(guanylhydrazone) dihydrochloride
    Molecular Weight:
    257.13
    Molecular Formula:
    C5H12N8 2HCl
    Solubility:
    Soluble in Water (greater than 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Confirms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • POB | Ornithine decarboxylase inhibitor
    CAS:
    946135-39-3
    Catalog Number:
    10-4553
    Activity:
    Ornithine decarboxylase inhibitor
    Chemical Name:
    N-(4′-Pyridoxyl)-L-Ornithine(BOC)-Ome
    Molecular Weight:
    397.47
    Molecular Formula:
    C19H31N3O6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), in Water (up to 2 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Confirms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. Solutions in distilled water are not stable and must be made fresh and used within one working day.
    Shipping Code:
    RT
  • Difluoromethylornithine HCl | Inhibits polyamine biosynthesis
    CAS:
    96020-91-6
    Catalog Number:
    10-2274
    Activity:
    Inhibits polyamine biosynthesis
    Alternate Names:
    DFMO; Eflornithine
    Chemical Name:
    DL-α-Difluoromethylornithine Hydrochloride Monohydrate
    Molecular Weight:
    236.65
    Molecular Formula:
    C6H12F2N2O2 HCl H2O
    Solubility:
    Soluble in Water (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Polyamine Products

Sphingolipids

  • L-Cycloserine | Serine palmitoyltransferase inhibitor
    CAS:
    339-72-0
    Catalog Number:
    10-2280
  • PF-543 HCl | Sphingosine kinase-1 inhibitor
    CAS:
    1706522-79-3
    Catalog Number:
    10-4998
  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • NVP-231 | Ceramide kinase inhibitor
    CAS:
    362003-83-6
    Catalog Number:
    10-4694
    Activity:
    Reversible ceramide kinase inhibitor
    Chemical Names:
    N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
    Molecular Weight:
    431.55
    Molecular Formula:
    C25H25N3O3S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Perphenazine | Antipsychotic agent
    CAS:
    58-39-9
    Catalog Number:
    10-4709
    Activity:
    Typical antipsychotic
    Chemical Name:
    2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
    Molecular Weight:
    403.98
    Molecular Formula:
    C21H26ClN3OS
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Sphingolipids Products

Trans-Sulfuration

  • Intelliscreen™ Cancer Cell Metabolism Library
    Catalog Number:
    10-7101
    Description:
    171 modulators of various aspects of cancer cell metabolism.
    Solubility:
    DMSO or Water
    Supplied As:
    Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $4 600.00
  • PF-9366 | Methionine adenosyltransferase 2A inhibitor
    CAS:
    72882-78-1
    Catalog Number:
    10-4635
    Activity:
    Methionine adenosyltransferase 2A inhibitor
    Chemical Name:
    2-(7-Chloro-5-phenyl)-[1,2,4]triazolo[4,3-a]quinoline-1-yl)-N,N,dimethylethanamine
    Molecular Weight:
    350.85
    Molecular Formula:
    C20H19ClN4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Propargylglycine | H2S synthase inhibitor
    CAS:
    64165-64-6
    Catalog Number:
    10-1366
    Activity:
    H2S synthase inhibitor
    Chemical Name:
    2-Amino-4-pentynoic acid
    Molecular Weight:
    113.12
    Molecular Formula:
    C5H7NO2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Water (up tp 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Trans-Sulfuration Products

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Plymouth Meeting, PA USA
1-855-FOCUS21

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