Neurosciences

Focus Biomolecules research products for neuroscience include modulators of targets including ion channels, nitric oxide pathways, neurotransmitters, lipid signaling, cannabinoids, epigenetics; for areas such as neurodegeneration, pain, mood disorders, neuroinflammation, addiction, memory, and more.

Addiction

  • SBI-553 | ß-Arrestin-biased NTSR1 modulator
    CAS:
    1849603-72-0
    Catalog Number:
    10-4449
  • Varenicline tartrate | α4ß2 partial agonist/Smoking cessation aid
    CAS:
    375815-87-5
    Catalog Number:
    10-2362
  • KNK437 | HSP70 inhibitor
    CAS:
    218924-25-5
    Catalog Number:
    10-5561
    Activity:
    HSP70 inhibitor
    Chemical Names:
    3-(1,3-Benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde
    Molecular Weight:
    245.23
    Molecular Formula:
    C13H11NO4
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Flumazenil | Benzodiazepine antagonist
    CAS:
    78755-81-4
    Catalog Number:
    10-1081
    Activity:
    Benzodiazepine antagonist
    Chemical Name:

    8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester

    Alternate Names:

    Ro 1722;  Ro 15-1788

    Molecular Weight:
    303.29
    Molecular Formula:
    C15H14FN3O3
    Solubility:
    Soluble in DMSO (up to 8 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • JNJ-63533054 | GPR139 agonist, suppresses morphine intake
    CAS:
    180232666-4
    Catalog Number:
    10-3880
    Activity:
    GPR139 agonist, suppresses morphine intake
    Chemical Name:
    (S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl) benzamide
    Molecular Weight:
    316.78
    Molecular Formula:
    C17H17ClN2O2
    Solubility:
    Soluble in DMSO (up to 35 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
View All Addiction Products

Cannabinoids

  • Oleamide | Endogenous sleep-inducing lipid
    CAS:
    301-02-0
    Catalog Number:
    10-2923
    Activity:
    Endogenous sleep-inducing lipid
    Chemical Names:
    9Z-Octadecenamide; cis-9-Octadecenamide; Oleic acid amide
    Molecular Weight:
    281.48
    Molecular Formula:
    C18H35NO
    Solubility:
    Soluble in DMSO (25 mg/ml); Ethanol (40 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    99% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • AM251 | Cannabinoid CB1 antagonist
    CAS:
    183232-66-8
    Catalog Number:
    10-2007
    Activity:
    Cannabinoid CB1 receptor antagonist
    Chemical Name:
    N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
    Molecular Weight:
    555.24
    Molecular Formula:
    C22H21Cl2IN4O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 13 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Anandamide | Endogenous cannabinoid
    CAS:
    94421-68-8
    Catalog Number:
    10-2009
    Activity:
    Endogenous cannabinoid
    Alternate Names:
    Arachidonoylethanolamide; AEA
    Chemical Name:
    N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
    Molecular Weight:
    347.54
    Molecular Formula:
    C22H27NO2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 50 mg/ml).
    Physical Properties:
    Colorless oil
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -80°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Subject to oxidation – protect from air. Solutions in degassed DMSO or ethanol may be stored under nitrogen or argon at -80°C for up to 1 month.
    Shipping Code:
    Blue Ice
  • Palmitoylethanolamide | GPR55 agonist
    CAS:
    544-31-0
    Catalog Number:
    10-1297
    Activity:
    GPR55 agonist
    Alternate Names:
    PEA
    Chemical Name:
    N-(2-Hydroxyethyl)palmitamide
    Molecular Weight:
    299.49
    Molecular Formula:
    C18H37NO2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • SR-144528 | Cannabinoid CB2 antagonist
    CAS:
    192703-06-3
    Catalog Number:
    10-1164
    Activity:
    Cannabinoid CB2 antagonist
    Chemical Name:
    5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide
    Molecular Weight:
    476.07
    Molecular Formula:
    C29H34ClN3O
    Solubility:
    Soluble in DMSO (up to 20 mg/ml, with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Cannabinoids Products

Epigenetics

  • BG45 | HDAC3 selective inhibitor
    CAS:
    926259-99-6
    Catalog Number:
    10-5638
  • TTK21 | CBP/p300 histone acetyltransferase activator
    CAS:
    709676-56-2
    Catalog Number:
    10-5669
    Activity:
    Histone acetyltransferase CBP/p300 activator
    Chemical Names:
    N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-propoxybenzamide
    Molecular Weight:
    357.76
    Molecular Formula:
    C17H15ClF3NO2
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • JQ1 (+) | BET Bromodomain inhibitor
    CAS:
    1268524-70-4
    Catalog Number:
    10-1584
    Activity:
    BET Bromodomain inhibitor
    Chemical Name:
    (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
    Molecular Weight:
    456.99
    Molecular Formula:
    C23H25ClN4O2S
    Solubility:
    Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 46 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
  • Triacetyl resveratrol | SIRT activator, prodrug
    CAS:
    42206-94-0
    Catalog Number:
    10-2437
    Activity:
    SIRT activator, prodrug
    Chemical Name:
    5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate
    Alternate Names:
    3,5,4’-Tri-O-acetylresveratrol
    Molecular Weight:
    364.43
    Molecular Formula:
    C20H28O6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in ethanol (up to 8 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • UNC1999 | Methyltransferase inhibitor
    CAS:
    1431612-23-5
    Catalog Number:
    10-4542
    Activity:
    Methyltransferase inhibitor
    Chemical Name:
    N-[(6-Methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxamide
    Molecular Weight:
    569.74
    Molecular Formula:
    C33H43N7O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Epigenetics Products

Ion channels

  • Arvanil | TRPV1 channel activator
    CAS:
    128007-31-8
    Catalog Number:
    10-2741
  • CBA | TRPM4 blocker
    CAS:
    351424-20-9
    Catalog Number:
    10-3643
  • PBMC·HCl | TRPM8 blocker
    CAS:
    1352138-54-5 (free base)
    Catalog Number:
    10-5707
    Activity:
    TRPM8 blocker
    Chemical Name:
    (S)-1-Phenylethyl(2-aminoethyl)(4-(benzyloxy)-3-methoxybenzyl)carbamate hydrochloride
    Molecular Weight:
    471.00
    Molecular Formula:
    C26H30N2O4·HCl
    Solubility:
    Soluble in DMSO (up to 30 mg/ml); water (10 mg/ml).
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • CBD3063 | Cav2.2 blocker
    CAS:
    1281060-70-5
    Catalog Number:
    10-4954
  • ML133 | Kir2 potassium channel blocker
    CAS:
    1222781-70-5
    Catalog Number:
    10-5098
View All Ion channels Products

Memory and learning

  • Linopirdine dihydrochloride | Kv7 Blocker
    CAS:
    113168-57-3
    Catalog Number:
    10-4654
  • Probucol | Antioxidant hypercholesterolemic agent
    CAS:
    23288-49-5
    Catalog Number:
    10-2679
  • Nimodipine | L-type calcium channel blocker
    CAS:
    66085-59-4
    Catalog Number:
    10-1321
    Activity:
    L-type calcium channel blocker
    Chemical Name:
    1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methyloxyethyl 1-methylethyl ester
    Alternate Names:
    BAY-e 9736
    Molecular Weight:
    418.44
    Molecular Formula:
    C21H26N2O7
    Solubility:
    Soluble in DMSO (up to 40 mg/ml)
    Physical Properties:
    Pale-yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • RGFP966 | Selective HDAC3 inhibitor
    CAS:
    1357389-11-7
    Catalog Number:
    10-4029
    Activity:
    Selective HDAC3 inhibitor
    Chemical Name:
    (2E)-N-(2-Amino-4-fluorophenyl)-3-[(2E)-1-(3-phenyl-2-propen-1-yl)-1H-pyrazol-4-yl]-2-propenamide
    Molecular Weight:
    362.40
    Molecular Formula:
    C21H19FN4O
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Roflumilast | PDE4 inhibitor
    CAS:
    162401-32-3
    Catalog Number:
    10-2657
    Activity:
    PDE4 inhibitor
    Chemical Name:
    3(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-benzamide
    Alternate Names:
    BYK-20869
    Molecular Weight:
    403.21
    Molecular Formula:
    C17H14N2Cl2F2O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Memory and learning Products

Neural stem cells

  • Dibutyryl cAMP | Cell permeable cAMP
    CAS:
    16980-89-5
    Catalog Number:
    10-2627
    Activity:
    Cell permeable cAMP
    Chemical Name:
    N6,O2′-Dibutyryl adenosine 3′,5′-cyclic monophosphate sodium salt
    Alternate Name:
    Bucladesine Na
    Molecular Weight:
    491.37
    Molecular Formula:
    C18H23N5O8P ∙ Na
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in water (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Fluoxetine HCl | Serotonin reuptake inhibitor
    CAS:
    56296-78-7
    Catalog Number:
    10-2728
    Activity:
    Serotonin reuptake inhibitor
    Chemical Name:
    (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride
    Alternate Names:
    LY-110,140
    Molecular Weight:
    345-79
    Molecular Formula:
    C17H18F3NO • HCl
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Water (up to 4 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Rufinamide | Anticonvulsant / Improves cognition
    CAS:
    106308-44-5
    Catalog Number:
    10-4275
    Activity:
    Anticonvulsant / Improves cognition
    Chemical Name:
    1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
    Molecular Weight:
    238.19
    Molecular Formula:
    C10H8F2N4O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Deltamethrin | Calcineurin inhibitor/displays neurotrophic activity
    CAS:
    52918-63-5
    Catalog Number:
    10-3103
    Activity:
    Calcineurin inhibitor; displays neurotrophic activity
    Chemical Name:
    (S)-α-Cyano-3-phenoxybenzyl (1R, 3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
    Molecular Weight:
    505.20
    Molecular Formula:
    C22H19Br2NO3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC and GC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Prostratin | Promotes neuro-regeneration
    CAS:
    60857-08-1
    Catalog Number:
    10-2169
    Activity:
    Promotes neuro-regeneration
    Chemical Name:
    13-O-Acetyl-12-deoxyphorbol
    Alternate Names:
    12-Deoxyphorbol 13-Acetate; dPAc
    Molecular Weight:
    390.47
    Molecular Formula:
    C22H30O6
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Neural stem cells Products

Neurodegeneration

View All Neurodegeneration Products

Neuroinflammation

  • TPPU | Soluble epoxide hydrolase inhibitor
    CAS:
    1222780-33-7
    Catalog Number:
    10-3451
  • Muscone | Cardioprotective and neuroprotective agent
    CAS:
    541-91-3
    Catalog Number:
    10-2757
  • P7C3-A20 | NAMPT activator/Proneurogenic agent
    CAS:
    1235481-90-9
    Catalog Number:
    10-3414
    Activity:
    NAMPT activator/proneurogenic agent
    Chemical Names:
    3,6-Dibromo-ß-fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine
    Molecular Weight:
    506.21
    Molecular Formula:
    C22H19Br2FN2O
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • PLX5622 | Highly selective CSF1R inhibitor
    CAS:
    1303420-67-8
    Catalog Number:
    10-4726
    Activity:
    Highly selective CSF1R inhibitor
    Chemical Names:
    6-Fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)methyl]pyridine-2-amine
    Molecular Weight:
    395.41
    Molecular Formula:
    C21H19F2N5O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Laquinimod | Immunomodulator
    CAS:
    248281-84-7
    Catalog Number:
    10-4971
    Activity:
    Immunomodulator
    Chemical Names:
    5-Chloro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide
    Alternate Name:
    ABR-215062
    Molecular Weight:
    356.81
    Molecular Formula:
    C19H17ClN2O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Neuroinflammation Products

Neuroprotection

  • Arvanil | TRPV1 channel activator
    CAS:
    128007-31-8
    Catalog Number:
    10-2741
  • Blebbistatin | Non-muscle myosin II inhibitor
    CAS:
    674289-55-5
    Catalog Number:
    10-2832
  • CBA | TRPM4 blocker
    CAS:
    351424-20-9
    Catalog Number:
    10-3643
  • PF-4708671 dihydrochloride | S6K1 inhibitor
    CAS:
    125517-76-0 (free base)
    Catalog Number:
    10-4856
    Activity:
    S6K1 inhibitor
    Chemical Names:
    2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzimidazole dihydrochloride
    Molecular Weight:
    463.33
    Molecular Formula:
    C19H21F3N6·2HCl
    Solubility:
    Soluble in DMSO (at least 35 mg/ml); Water (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month. Hygroscopic solid – protect from moisture.
    Shipping Code:
    RT
  • ML133 | Kir2 potassium channel blocker
    CAS:
    1222781-70-5
    Catalog Number:
    10-5098
View All Neuroprotection Products

Neurotransmitters

  • Ketanserin tartrate | Serotonin 5-HT2A antagonist
    CAS:
    83846-83-7
    Catalog Number:
    10-2490
  • 6,7-ADTN HBr | Dopamine receptor agonist
    CAS:
    13575-86-5
    Catalog Number:
    10-1607
  • Dihydroergotamine mesylate | Vascular serotonin receptor agonist
    CAS:
    6190-39-2
    Catalog Number:
    10-3400
    Activity:
    Vascular serotonin receptor agonist
    Chemical Names:
    (5’a,10a)-9,10-Dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)ergotaman-3′,6′,18-trione, mesylate
    Molecular Weight:
    679.79
    Molecular Formula:
    C33H37N5O5·CH3SO3H
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Bupropion HCl | Monoamine transporter inhibitor
    CAS:
    31677-93-7
    Catalog Number:
    10-2462
    Activity:
    Monoamine transporter inhibitor
    Chemical Names:
    1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride
    Molecular Weight:
    276.20
    Molecular Formula:
    C13H18ClNO·HCl
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Reserpine | VMAT1,2 inhibitor
    CAS:
    50-55-5
    Catalog Number:
    10-2689
    Activity:
    VMAT1 and 2 inhibitor
    Chemical Names:
    (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester; NSC59272
    Molecular Weight:
    608.68
    Molecular Formula:
    C33H40N2O9
    Solubility:
    Soluble in DMSO (35 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Neurotransmitters Products

Neurovascular/BBB

  • CK-666 | ARP2/3 inhibitor
    CAS:
    442633-00-3
    Catalog Number:
    10-3346
    Activity:
    ARP2/3 inhibitor
    Chemical Name:
    2-Fluoro-N-[2-methyl-1H-indol-3-yl)ethyl]benzamide
    Molecular Weight:
    296.34
    Molecular Formula:
    C18H17FN2O
    Solubility:
    Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 30 mg/ml)
    Physical Properties:
    Cream-colored solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Enzastaurin | PKC inhibitor
    CAS:
    170364-57-5
    Catalog Number:
    10-2132
    Activity:
    PKC inhibitor
    Chemical Name:
    3-(1-Methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione
    Alternate Names:
    LY-317615
    Molecular Weight:
    515.61
    Molecular Formula:
    C32H29N5O2
    Solubility:
    Soluble in DMSO (up to 7 mg/ml with warming)
    Physical Properties:
    Orange solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Ibudilast | Neuroinflammation inhibitor
    CAS:
    50847-11-5
    Catalog Number:
    10-2236
    Activity:
    Neuroinflammation inhibitor
    Chemical Name:
    3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine
    Alternate Names:
    2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridine-3-yl 1-propanone; KC-404; AV411
    Molecular Weight:
    230.31
    Molecular Formula:
    C14H18N2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or Ethanol (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Vinpocetine | PDE1 inhibitor
    CAS:
    42971-09-5
    Catalog Number:
    10-1126
    Activity:
    PDE1 inhibitor
    Chemical Name:
    (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
    Molecular Weight:
    350.45
    Molecular Formula:
    C22H26N2O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml), in ethanol (up to 15 mg/ml) or in DMF (up to 3 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, Ethanol, or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Neurovascular/BBB Products

Other Neurosciences

  • TLX agonist 31 | TLX agonist
    CAS:
    3055146-41-0
    Catalog Number:
    10-3945
  • MU1700 | Selective ALK1/2 inhibitor
    CAS:
    1360905-04-9 (free base)
    Catalog Number:
    10-4746
  • TH257 | Allosteric LIM kinase inhibitor
    CAS:
    2244678-29-1
    Catalog Number:
    10-4418
    Activity:
    Allosteric LIM kinase inhibitor
    Chemical Names:
    N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide
    Molecular Weight:
    422.54
    Molecular Formula:
    C24H26N2O3S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White to off-white glassy solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • NQDI-1 | ASK1 inhibitor
    CAS:
    175026-96-7
    Catalog Number:
    10-5144
    Activity:
    ASK1 inhibitor
    Chemical Names:
    2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid, ethyl ester
    Molecular Weight:
    319.31
    Molecular Formula:
    C19H13NO4
    Solubility:
    Soluble in DMSO ( up to 3 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Pseurotin A | Fungal metabolite with neuritogenic activity
    CAS:
    58523-30-1
    Catalog Number:
    10-2630
    Activity:
    Fungal metabolite with potent neuritogenic activity
    Chemical Names:
    Fermentation product of Aspergillus fumigatus
    Molecular Weight:
    431.44
    Molecular Formula:
    C22H25NO8
    Solubility:
    Soluble in DMSO (10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Other Neurosciences Products

Pain

  • Arvanil | TRPV1 channel activator
    CAS:
    128007-31-8
    Catalog Number:
    10-2741
  • GAT2711 | α9 nAChR agonist
    CAS:
    N/A
    Catalog Number:
    10-4330
  • PBMC·HCl | TRPM8 blocker
    CAS:
    1352138-54-5 (free base)
    Catalog Number:
    10-5707
    Activity:
    TRPM8 blocker
    Chemical Name:
    (S)-1-Phenylethyl(2-aminoethyl)(4-(benzyloxy)-3-methoxybenzyl)carbamate hydrochloride
    Molecular Weight:
    471.00
    Molecular Formula:
    C26H30N2O4·HCl
    Solubility:
    Soluble in DMSO (up to 30 mg/ml); water (10 mg/ml).
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • CBD3063 | Cav2.2 blocker
    CAS:
    1281060-70-5
    Catalog Number:
    10-4954
  • eFT508 | Potent MNK1/2 inhibitor
    CAS:
    1849590-01-7
    Catalog Number:
    10-4081
View All Pain Products

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