Proteases

Proteases hydrolyze α-peptide bonds of proteins, either at the terminal amino acid (exoprotease) or an internal amino acid (endoprotease). Some proteases instead cleave isopeptide bonds (e.g. DUBs) or γ-glutamyl bonds (e.g. glutamate carboxypeptidase). Proteases play roles in development, wound healing, pregnancy, and many other processes, making them therapeutic targets for diseases such as cancer, inflammation, and infectious disease.

ACE

  • Captopril | Angiotensin-converting enzyme inhibitor
    CAS:
    62571-86-2
    Catalog Number:
    10-2253
    Activity:
    Angiotensin-converting enzyme inhibitor
    Chemical Name:
    (2S)-1-(3-Mercapto-2-methyl-propionyl)-L-proline
    Molecular Weight:
    217.28
    Molecular Formula:
    C9H15NO3S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month
    Shipping Code:
    RT
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ADAM

  • 1,10-Phenanthroline HCl | Zn metalloprotease inhibitor
    CAS:
    3829-86-5
    Catalog Number:
    10-3017
    Activity:
    Zn metalloprotease inhibitor
    Alternate Names:
    o-Phenanthroline hydrochloride hydrate
    Molecular Weight:
    234.68
    Molecular Formula:
    C13H8N2 • HCl &bul; H2O
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Water (up to 2 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All ADAM Products

Aminopeptidases

  • gamma-L-Glutamyl-p-nitroanilide HCl | L-Glutamine uptake inhibitor and gamma-glutamyl transpeptidase substrate
    CAS:
    67953-08-6
    Catalog Number:
    10-4568
    Activity:
    L-Glutamine uptake inhibitor and gamma-glutamyl transpeptidase substrate
    Alternate Names:
    GPNA
    Molecular Weight:
    303.7
    Molecular Formula:
    C11H13N3O5 HCl
    Solubility:
    Soluble in Water (up to 5 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Actinonin | Leucyl aminopeptidase inhibitor
    CAS:
    13434-13-4
    Catalog Number:
    10-2549
    Activity:
    Leucyl aminopeptidase inhibitor
    Chemical Name:
    3-[[1-[-2-Hydroxymethyl)-1-pyrrolidinyl)carbonyl]-2-methylpropyl]carbamoyl]-octanohydroxamic acid
    Molecular Weight:
    385.51
    Molecular Formula:
    C19H36N3O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
  • Puromycin | Translation inhibitor
    CAS:
    58-58-2
    Catalog Number:
    10-2100
    Activity:
    Translation inhibitor
    Chemical Name:
    (S)-3′-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]-amino]-3′-deoxy-N,N-dimethyl-adenosine dihydrochloride
    Molecular Weight:
    544.43
    Molecular Formula:
    C22H29N7O5 2HCl
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Bestatin HCl | Aminopeptidase inhibitor
    CAS:
    65391-42-6
    Catalog Number:
    10-1286
    Activity:
    Aminopeptidase inhibitor
    Chemical Name:
    [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine HCl
    Molecular Weight:
    344.84
    Molecular Formula:
    C16H24N2O4 HCl
    Solubility:
    Soluble in Water (up to 10 mg/ml). Also soluble in DMSO and Ethanol.
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, distilled water, or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
View All Aminopeptidases Products

Calpains

  • MDL-28170 | Calpain inhibitor
    CAS:
    88191-84-8
    Catalog Number:
    10-3005
    Activity:
    Calpain inhibitor
    Chemical Name:
    N-Benzyloxycarbonylvalylphenylalaninal
    Alternate Name:
    Z-Val-Phe-CHO; Calpain Inhibitor III
    Molecular Weight:
    382.45
    Molecular Formula:
    C22H26N2O4
    Solubility:
    Soluble in DMSO (up to 75 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • E-64d | Cysteine protease inhibitor
    CAS:
    88321-09-9
    Catalog Number:
    10-1347
    Activity:
    Cysteine protease inhibitor
    Chemical Name:
    2S,3S-trans-(Ethoxycarbonyloxirane-2-carbonyl)-L-leucine-(3-methylbutyl)amide
    Molecular Weight:
    342.43
    Molecular Formula:
    C17H30N2O5
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • ALLN | Calpain inhibitor
    CAS:
    110044-82-1
    Catalog Number:
    10-3024
    Activity:
    Calpain inhibitor
    Chemical Name:
    Ac-Leu-Leu-Nle-CHO
    Alternate Names:
    Ac-LL-norleucinal
    Molecular Weight:
    383.53
    Molecular Formula:
    C20H37N3O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • E-64 | Cysteine protease inhibitor
    CAS:
    66701-25-5
    Catalog Number:
    10-1345
    Activity:
    Cysteine protease inhibitor
    Chemical Name:
    (2S,3S)-trans-Epoxy succinyl-L-leucylamido-(4-guanidino)butane
    Molecular Weight:
    357.41
    Molecular Formula:
    C15H27N5O5
    Solubility:
    Soluble in a 1:1 mixture of Ethanol and Water (up to 20 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in 1:1 ethanol/water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • ALLM | Calpain inhibitor
    CAS:
    136632-32-1
    Catalog Number:
    10-1349
    Activity:
    Calpain inhibitor
    Chemical Name:
    N-Acetyl-Leu-Leu-Methional
    Alternate Names:
    Ac-LLM-CHO
    Molecular Weight:
    401.56
    Molecular Formula:
    C19H35N3O4S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Calpains Products

Carboxypeptidases

  • ZJ43 | Potent inhibitor of glutamate carboxypeptidases II and III
    CAS:
    723331-20-2
    Catalog Number:
    10-3904
    Activity:
    Potent inhibitor of glutamate carboxypeptidases II and III
    Chemical Name:
    N-[[[(1S)-1-Carboxy-3-methylbutyl]amino]carbonyl]-L-glutamic acid
    Molecular Weight:
    304.30
    Molecular Formula:
    C12H20N2O7
    Solubility:
    Soluble in DMSO (up to at least mg/ml) or in Water (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
View All Carboxypeptidases Products

Caspases

  • Z-DEVD-FMK | Caspase-3 inhibitor
    CAS:
    210344-95-9
    Catalog Number:
    10-2904
    Activity:
    Caspase-3 inhibitor
    Chemical Names:
    Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone
    Molecular Weight:
    668.67
    Molecular Formula:
    C30H41FN4O12
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    Lyophilized solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Emricasan | pan-Caspase inhibitor
    CAS:
    254750-02-2
    Catalog Number:
    10-4280
    Activity:
    pan-Caspase inhibitor
    Chemical Names:
    (3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid
    Alternate Name:
    IDN-6556; PF-03491390
    Molecular Weight:
    569.51
    Molecular Formula:
    C26H27F4N3O7
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • SM-164 | Smac mimetic
    CAS:
    957135-43-2
    Catalog Number:
    10-5464
    Activity:
    Smac mimetic
    Chemical Names:
    (3S,3′S,6S,6′S,10aS,10′aS)-N,N′-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamide
    Molecular Weight:
    1121.45
    Molecular Formula:
    C62H84N14O6
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    White to pale-yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Belnacasan | ICE/caspase-1 inhibitor
    CAS:
    273404-37-8
    Catalog Number:
    10-4399
    Activity:
    ICE/caspase-1 inhibitor
    Chemical Names:
    (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; VX-765
    Molecular Weight:
    508.99
    Molecular Formula:
    C24H33ClN4O6
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white to white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • PAC-1 | Procaspase activator
    CAS:
    315183-21-2
    Catalog Number:
    10-2979
    Activity:
    Procaspase activator
    Chemical Name:
    4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]-methylene]hydrazide
    Molecular Weight:
    392.49
    Molecular Formula:
    C23H28N4O2
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol must be stored under inert gas at -80°C and will be stable for up to 2 months.
    Shipping Code:
    RT
View All Caspases Products

Cathepsins

  • SSAA09E1 | SARS-CoV viral entry inhibitor
    CAS:
    433212-75-0
    Catalog Number:
    10-5075
    Activity:
    SARS-CoV viral entry inhibitor
    Chemical Names:
    [(Z)-1-Thiophene-2-ylethylideneamino]thiourea
    Molecular Weight:
    199.29
    Molecular Formula:
    C17H9N3S2
    Solubility:
    Soluble in DMSO (100 mg/ml); ethanol (10 mg/ml with warming
    Physical Properties:
    Beige solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years at-20°C from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Z-Leu-Arg-AMC | Fluorogenic Cathepsin K substrate
    CAS:
    156192-32-4
    Catalog Number:
    10-5386
    Activity:
    Fluorogenic cathepsin substrate
    Alternate Name:
    Z-LR-AMC hydrochloride; Cbz-Leu-Arg-AMC hydrochloride
    Molecular Weight:
    615.13
    Molecular Formula:
    C30H38N6O6·HCl
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >97% HPLC
    Amino acid analysis and identity: Confirmed
    Peptide content:
    93%
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. Protect from light!
    Shipping Code:
    RT
  • Z-Phe-Arg-AMC | Fluorogenic cathepsin substrate
    CAS:
    70382-26-2
    Catalog Number:
    10-5385
    Activity:
    Fluorogenic cathepsin substrate
    Alternate Name:
    Z-FR-AMC hydrochloride; Cbz-Phe-Arg-AMC hydrochloride
    Molecular Weight:
    619.14
    Molecular Formula:
    C33H36N6O6·HCl
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    Amino acid analysis and identity: Confirmed
    Peptide content:
    94%
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. Protect from light!
    Shipping Code:
    RT
  • E-64d | Cysteine protease inhibitor
    CAS:
    88321-09-9
    Catalog Number:
    10-1347
    Activity:
    Cysteine protease inhibitor
    Chemical Name:
    2S,3S-trans-(Ethoxycarbonyloxirane-2-carbonyl)-L-leucine-(3-methylbutyl)amide
    Molecular Weight:
    342.43
    Molecular Formula:
    C17H30N2O5
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Z-Phe-Tyr-CHO | Cathepsin L inhibitor
    CAS:
    167498-29-5
    Catalog Number:
    10-3079
    Activity:
    Cathepsin L inhibitor
    Alternate Names:
    Z-FY-CHO; Z-Phe-Tyr-Aldehyde; SB-412515
    Molecular Weight:
    446.50
    Molecular Formula:
    C26H26N2O5
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 50 mg/ml)
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Cathepsins Products

Chymotrypsin

  • Z-Leu-Leu-Leu-vinylsulfone | Proteasome inhibitor
    CAS:
    193482-47-2
    Catalog Number:
    10-4990
  • Suc-Leu-Leu-Val-Tyr-AMC | Proteasome substrate
    CAS:
    94367-21-2
    Catalog Number:
    10-2971
    Activity:
    Proteasome substrate
    Alternate Names:
    Suc-LLVY-AMC, Proteasome Substrate III (Fluorogenic)
    Molecular Weight:
    763.88
    Molecular Formula:
    C40H53N5O10
    Solubility:
    Soluble in DMSO (up to 20 mg/ml), or in DMF (up to 10 mg/ml)
    Physical Properties:
    Lyophilized solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Chymostatin | Inhibitor of Chymotrypsin-like serine proteases
    CAS:
    9076-44-2
    Catalog Number:
    10-2722
    Activity:
    Inhibitor of chymotrypsin-like serine proteases
    Chemical Name:
    [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu, B=Val, C=Ile]-phenylalaninal
    Molecular Weight:
    605.0 (ave.)
    Molecular Formula:
    C31H41N7O6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • AEBSF HCl | Protease inhibitor
    CAS:
    30827-99-7
    Catalog Number:
    10-1348
    Activity:
    Protease inhibitor
    Chemical Name:
    4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
    Molecular Weight:
    239.69
    Molecular Formula:
    C8H10FNO2S • HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to 100 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions at pH <7 are stable for up to 6 months if stored in the refrigerator
    Shipping Code:
    RT
  • TPCK | Serine protease inhibitor
    CAS:
    402-71-1
    Catalog Number:
    10-2290
    Activity:
    Serine protease inhibitor
    Chemical Name:
    N-p-Tosyl-L-phenylalanine chloromethyl ketone
    Molecular Weight:
    351.8
    Molecular Formula:
    C17H18ClNO3S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Chymotrypsin Products

Coagulation proteases

  • Apixaban | Factor Xa inhibitor
    CAS:
    503612-47-3
    Catalog Number:
    10-5660
    Activity:
    Factor Xa inhibitor
    Chemical Names:
    4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
    Molecular Weight:
    459.51
    Molecular Formula:
    C25H25N5O4
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
View All Coagulation proteases Products

Cysteine proteases

  • Z-Leu-Arg-AMC | Fluorogenic Cathepsin K substrate
    CAS:
    156192-32-4
    Catalog Number:
    10-5386
    Activity:
    Fluorogenic cathepsin substrate
    Alternate Name:
    Z-LR-AMC hydrochloride; Cbz-Leu-Arg-AMC hydrochloride
    Molecular Weight:
    615.13
    Molecular Formula:
    C30H38N6O6·HCl
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >97% HPLC
    Amino acid analysis and identity: Confirmed
    Peptide content:
    93%
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. Protect from light!
    Shipping Code:
    RT
  • Z-Phe-Arg-AMC | Fluorogenic cathepsin substrate
    CAS:
    70382-26-2
    Catalog Number:
    10-5385
    Activity:
    Fluorogenic cathepsin substrate
    Alternate Name:
    Z-FR-AMC hydrochloride; Cbz-Phe-Arg-AMC hydrochloride
    Molecular Weight:
    619.14
    Molecular Formula:
    C33H36N6O6·HCl
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    Amino acid analysis and identity: Confirmed
    Peptide content:
    94%
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. Protect from light!
    Shipping Code:
    RT
  • MDL-28170 | Calpain inhibitor
    CAS:
    88191-84-8
    Catalog Number:
    10-3005
    Activity:
    Calpain inhibitor
    Chemical Name:
    N-Benzyloxycarbonylvalylphenylalaninal
    Alternate Name:
    Z-Val-Phe-CHO; Calpain Inhibitor III
    Molecular Weight:
    382.45
    Molecular Formula:
    C22H26N2O4
    Solubility:
    Soluble in DMSO (up to 75 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • E-64d | Cysteine protease inhibitor
    CAS:
    88321-09-9
    Catalog Number:
    10-1347
    Activity:
    Cysteine protease inhibitor
    Chemical Name:
    2S,3S-trans-(Ethoxycarbonyloxirane-2-carbonyl)-L-leucine-(3-methylbutyl)amide
    Molecular Weight:
    342.43
    Molecular Formula:
    C17H30N2O5
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • ALLN | Calpain inhibitor
    CAS:
    110044-82-1
    Catalog Number:
    10-3024
    Activity:
    Calpain inhibitor
    Chemical Name:
    Ac-Leu-Leu-Nle-CHO
    Alternate Names:
    Ac-LL-norleucinal
    Molecular Weight:
    383.53
    Molecular Formula:
    C20H37N3O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Cysteine proteases Products

Dipeptidases

  • 1G244 | DPP8/9 inhibitor
    CAS:
    847928-32-9
    Catalog Number:
    10-4584
    Activity:
    DPP8/9 inhibitor
    Chemical Names:
    (S)-2-Amino-4-{4-[bis-(4-fluorophenyl)-methyl]piperazin-1-yl}-1-(1,3-dihydro-isoindol-2-yl)-butane-1,4-dione
    Alternate Name:
    PTX-1210
    Molecular Weight:
    504.57
    Molecular Formula:
    C29H30F2N4O2
    Solubility:
    Soluble in DMSO (>20 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Saxagliptin HCl | DPP-IV inhibitor
    CAS:
    709031-78-7
    Catalog Number:
    10-4076
    Activity:
    DPP-IV inhibitor
    Chemical Names:
    (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride; BMS-477118
    Molecular Weight:
    416.45
    Molecular Formula:
    C18H25N3O2·HCl
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Talabostat mesylate | Pyroptosis inducer / Inflammasome activator
    CAS:
    150080-09-4
    Catalog Number:
    10-4005
    Activity:
    Pyroptosis inducer / Inflammasome activator
    Chemical Name:
    ((2R)-1-((2S)-2-Amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic acid methanesulfonate
    Alternate Names:
    Val-boroPro; PT-100
    Molecular Weight:
    310.18
    Molecular Formula:
    C9H19BN2O3 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml); water (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Vildagliptin Supplier | DPPIV inhibitor
    CAS:
    274901-16-5
    Catalog Number:
    10-2887
    Activity:
    DPP4 inhibitor
    Chemical Name:
    (S)-1-[N-(3-Hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile
    Alternate Names:
    LAF237
    Molecular Weight:
    303.40
    Molecular Formula:
    C17H25N3O2
    Solubility:
    Soluble in DMSO (up to 45 mg/ml), in DMF (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 3 months
    Shipping Code:
    RT
  • P32/98 | DPPIV inhibitor
    CAS:
    136259-20-6
    Catalog Number:
    10-1142
    Activity:
    DPPIV inhibitor
    Alternate Names:
    Isoleucine thiazolidide hemi-fumarate
    Chemical Name:
    (2S,3S)-2-Amino-3-methyl-1-(thiazolidin-3-yl)pentan-1-one hemi-fumarate
    Molecular Weight:
    260.36
    Molecular Formula:
    C9H18N2OS·1/2(C4H4O4)
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Dipeptidases Products

FactorX

  • PKSI-527 | Selective plasma kallikrein inhibitor
    CAS:
    128837-71-8
    Catalog Number:
    10-2220
    Activity:
    Selective plasma kallikrein inhibitor
    Chemical Names:
    trans-4-Aminomethylcyclohexanecarbonyl-phenylalanyl-4-carboxymethylanilide
    Molecular Weight:
    474.01
    Molecular Formula:
    C25H31N3O4·HCl
    Solubility:
    Soluble in Water (5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All FactorX Products

gamma Secretase

  • DAPT | gamma-secretase inhibitor
    CAS:
    208255-80-5
    Catalog Number:
    10-4514
    Activity:
    γ-secretase inhibitor
    Alternate Names:
    LY-374973
    Chemical Name:
    N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester
    Molecular Weight:
    432.46
    Molecular Formula:
    C23H26F2N2O4
    Solubility:
    Soluble in DMSO (up to 18 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All gamma Secretase Products

Metalloproteases

  • Doxycycline monohydrate | Broad spectrum antibiotic
    CAS:
    17086-28-1
    Catalog Number:
    10-3765
  • Phosphoramidon | Neutral endopeptidase inhibitor
    CAS:
    119942-99-3
    Catalog Number:
    10-2548
    Activity:
    Neutral endopeptidase inhibitor
    Chemical Name:
    N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan•2Na
    Molecular Weight:
    587.47
    Molecular Formula:
    C23H32N3O10P • 2Na
    Solubility:
    Soluble in DMSO, methanol, or distilled water
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, methanol, or distilled water may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Batimastat | Matrix metalloprotease inhibitor (pan-specific)
    CAS:
    130370-60-4
    Catalog Number:
    10-1589
    Activity:
    Matrix metalloproteinase inhibitor (pan-specific)
    Chemical Name:
    (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamine)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
    Alternate Names:
    BB-94
    Molecular Weight:
    477.64
    Molecular Formula:
    C23H31N3O4S2
    Solubility:
    Soluble in DMSO (up to 45 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • 1,10-Phenanthroline HCl | Zn metalloprotease inhibitor
    CAS:
    3829-86-5
    Catalog Number:
    10-3017
    Activity:
    Zn metalloprotease inhibitor
    Alternate Names:
    o-Phenanthroline hydrochloride hydrate
    Molecular Weight:
    234.68
    Molecular Formula:
    C13H8N2 • HCl &bul; H2O
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Water (up to 2 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • NSC405020 | MT-MMP inhibitor
    CAS:
    7497-07-6
    Catalog Number:
    10-1462
    Activity:
    MT-MMP inhibitor
    Chemical Name:
    3,4-Dichloro-N-(1-methylbutyl)benzamide
    Molecular Weight:
    260.15
    Molecular Formula:
    C12H15NCl2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Metalloproteases Products

MetAP2

  • Fumagillin | MetAP-2 inhibitor
    CAS:
    23110-15-8
    Catalog Number:
    10-1146
    Activity:
    MetAP-2 inhibitor
    Chemical Name:
    (2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid ester
    Molecular Weight:
    458.54
    Molecular Formula:
    C26H34>/sub>O7
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Orange solid
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All MetAP2 Products

Neprilysin

  • Phosphoramidon | Neutral endopeptidase inhibitor
    CAS:
    119942-99-3
    Catalog Number:
    10-2548
    Activity:
    Neutral endopeptidase inhibitor
    Chemical Name:
    N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan•2Na
    Molecular Weight:
    587.47
    Molecular Formula:
    C23H32N3O10P • 2Na
    Solubility:
    Soluble in DMSO, methanol, or distilled water
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, methanol, or distilled water may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
View All Neprilysin Products

Neutrophil elastase

  • Elastatinal | Elastase inhibitor
    CAS:
    51798-45-9
    Catalog Number:
    10-2818
    Activity:
    Elastase inhibitor
    Chemical Name:
    N[(S)-1-Carboxyisopentyl]carbamoyl-a-[2-iminohexahydro-4(S)-pyrimidyl-(S)-glycl-(S)-glutaminyl-(S)-alaninal
    Molecular Weight:
    512.56
    Molecular Formula:
    C21H36N8O7
    Solubility:
    Soluble in DMSO (up to 3 mg/ml) or in Water (up to 5 mg/ml)
    Physical Properties:
    Lyophilized off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Sivelestat sodium | Leukocyte elastase inhibitor
    CAS:
    201677-61-4
    Catalog Number:
    10-1102
    Activity:
    Leukocyte elastase inhibitor
    Alternate Names:
    ONO-5046
    Chemical Name:
    N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium hydrate
    Molecular Weight:
    528.51
    Molecular Formula:
    C20H21N2O7S·Na·4H2O
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
    Shipping Code:
    RT
View All Neutrophil elastase Products

Other proteases

  • TIC10 | Mitochondrial caseinolytic protease P activator / Anticancer agent
    CAS:
    1616632-77-9
    Catalog Number:
    10-4090
    Activity:
    Mitochondrial caseinolytic protease P activator / Anticancer agent
    Chemical Name:
    7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one
    Alternate Name:
    ONC201
    Molecular Weight:
    386.49
    Molecular Formula:
    C24H26N4O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
  • Benzamidine HCl | Trypsin and serine protease inhibitor
    CAS:
    1670-14-0
    Catalog Number:
    10-2687
    Activity:
    Trypsin and serine protease inhibitor
    Chemical Name:
    Amidinobenzene hydrochloride
    Molecular Weight:
    156.61
    Molecular Formula:
    C7H8N2 • HCl
    Solubility:
    Soluble in water (up to 50 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily
    Shipping Code:
    RT
  • SIC5-6 | Separase inhibitor
    CAS:
    2410846-16-9
    Catalog Number:
    10-4075
    Activity:
    Separase inhibitor
    Chemical Name:
    3,3’-(1-((4-Iodophenyl)sulfonyl)piperidine-4,4’diyl)bis(1H-indole)
    Molecular Weight:
    581.47
    Molecular Formula:
    C27H24IN3O2S
    Solubility:
    Soluble in DMSO (up to at least 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Leu-Leu-OMe HBr | Lysosomal damaging agent
    CAS:
    16689-14-8
    Catalog Number:
    10-3220
    Activity:
    Lysosomal damaging agent
    Chemical Name:
    Leucyl-leucine methyl ester hydrobromide
    Alternate Names:
    LLME
    Molecular Weight:
    339.27
    Molecular Formula:
    C13H26N2O3 HBr
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Water (up to 40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • UCF-101 | Omi/HtrA2 protease inhibitor
    CAS:
    313649-08-0
    Catalog Number:
    10-1544
    Activity:
    Omi/HrtrA2 protease inhibitor
    Chemical Name:
    Dihydro-5[[5-(2-nitrophenyl)-2-furanyl]methylene]-1,3-diphenyl-2-thioxo-4,6(1H,5H)-pyrimidinedione
    Molecular Weight:
    495.51
    Molecular Formula:
    C27H17N3O5S
    Solubility:
    Soluble in DMSO (up to 30 mg/ml with warming) or in DMF (up to 25 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Other proteases Products

Proteasome

  • Z-Leu-Leu-Leu-vinylsulfone | Proteasome inhibitor
    CAS:
    193482-47-2
    Catalog Number:
    10-4990
  • Bz-Val-Gly-Arg-AMC | Proteasome substrate
    CAS:
    87779-49-5
    Catalog Number:
    10-2969
    Activity:
    Proteasome substrate
    Chemical Name:
    Benzoyl-Val-Gly-Arg-(7-amido-4-methylcoumarin)·trifluoroacetate
    Molecular Weight:
    705.7
    Molecular Formula:
    C30H37N7O6·CF3COOH
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Carfilzomib | Proteasome inhibitor
    CAS:
    868540-17-4
    Catalog Number:
    10-1477
    Activity:
    Proteasome inhibitor
    Alternate Names:
    PR-171
    Chemical Name:
    (αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]- L-Phenylalaninamide
    Molecular Weight:
    719.93
    Molecular Formula:
    C40H57N5O7
    Solubility:
    Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
  • P5091 | DUB USP7 inhibitor
    CAS:
    882257-11-6
    Catalog Number:
    10-1422
    Activity:
    DUB USP7 inhibitor
    Chemical Name:
    1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone
    Molecular Weight:
    348.23
    Molecular Formula:
    C12H7Cl2NO3S2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Epoxomicin | Irreversible 20S proteasome inhibitor
    CAS:
    134381-21-8
    Catalog Number:
    10-1384
    Activity:
    Irreversible 20S proteasome inhibitor
    Molecular Weight:
    554.73
    Molecular Formula:
    C28H50N4O7
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
View All Proteasome Products

Serine Proteases

  • Apixaban | Factor Xa inhibitor
    CAS:
    503612-47-3
    Catalog Number:
    10-5660
    Activity:
    Factor Xa inhibitor
    Chemical Names:
    4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
    Molecular Weight:
    459.51
    Molecular Formula:
    C25H25N5O4
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Gabexate mesylate | Serine Protease Inhibitor
    CAS:
    56974-61-9
    Catalog Number:
    10-2216
    Activity:
    Serine Protease Inhibitor
    Chemical Name:
    4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid, ethyl ester, methanesulfonate
    Alternate Name:
    FOY
    Molecular Weight:
    417.48
    Molecular Formula:
    C16H23N3O4 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Benzamidine HCl | Trypsin and serine protease inhibitor
    CAS:
    1670-14-0
    Catalog Number:
    10-2687
    Activity:
    Trypsin and serine protease inhibitor
    Chemical Name:
    Amidinobenzene hydrochloride
    Molecular Weight:
    156.61
    Molecular Formula:
    C7H8N2 • HCl
    Solubility:
    Soluble in water (up to 50 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily
    Shipping Code:
    RT
  • Camostat mesilate | Serine protease inhibitor/antiviral/anti-inflammatory
    CAS:
    59721-29-8
    Catalog Number:
    10-2196
    Activity:
    Serine protease inhibitor, antiviral, anti-inflammatory activity
    Chemical Name:
    4-(2-(2-(Dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate methanesulfonic acid salt
    Alternate Name:
    FOY-305; Foipan
    Molecular Weight:
    494.52
    Molecular Formula:
    C20H22N4O5 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or Water (up to 50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years  from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Chymostatin | Inhibitor of Chymotrypsin-like serine proteases
    CAS:
    9076-44-2
    Catalog Number:
    10-2722
    Activity:
    Inhibitor of chymotrypsin-like serine proteases
    Chemical Name:
    [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu, B=Val, C=Ile]-phenylalaninal
    Molecular Weight:
    605.0 (ave.)
    Molecular Formula:
    C31H41N7O6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Serine Proteases Products

Thrombin

  • Gabexate mesylate | Serine Protease Inhibitor
    CAS:
    56974-61-9
    Catalog Number:
    10-2216
    Activity:
    Serine Protease Inhibitor
    Chemical Name:
    4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid, ethyl ester, methanesulfonate
    Alternate Name:
    FOY
    Molecular Weight:
    417.48
    Molecular Formula:
    C16H23N3O4 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Argatroban | Thrombin inhibitor
    CAS:
    74863-84-6
    Catalog Number:
    10-2809
    Activity:
    Thrombin inhibitor
    Alternate Names:
    Argidipine; MQPA
    Chemical Name:
    (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid
    Molecular Weight:
    508.63
    Molecular Formula:
    C23H36N6O5S
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
View All Thrombin Products

Trypsin

  • Gabexate mesylate | Serine Protease Inhibitor
    CAS:
    56974-61-9
    Catalog Number:
    10-2216
    Activity:
    Serine Protease Inhibitor
    Chemical Name:
    4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid, ethyl ester, methanesulfonate
    Alternate Name:
    FOY
    Molecular Weight:
    417.48
    Molecular Formula:
    C16H23N3O4 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Leupeptin hemisulfate | Trypsin-like cysteine protease inhibitor
    CAS:
    103476-89-7
    Catalog Number:
    10-1346
    Activity:
    Trypsin-like cysteine protease inhibitor
    Alternate Names:
    Ac-Leu-Leu-Arg-CHO, hemisulfate
    Molecular Weight:
    475.59
    Molecular Formula:
    C20H38N6O4 &bul; 1/2H2SO4
    Solubility:
    Soluble in Water (up to 50 mg/ml). Also soluble in ethanol and methanol
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied Solutions in distilled water, ethanol or methanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Trypsin Products

Viral proteases

  • Asunaprevir | HCV NS3 protease inhibitor/CRISPR enhancer
    CAS:
    630420-16-5
    Catalog Number:
    10-4928
  • Atazanavir | HIV protease inhibitor
    CAS:
    198904-31-3
    Catalog Number:
    10-5630
    Activity:
    HIV protease inhibitor
    Chemical Names:
    Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
    Alternate Name:
    BMS 232632; CGP 73547; Latazanavir
    Molecular Weight:
    704.87
    Molecular Formula:
    C38H52N6O7
    Solubility:
    Soluble in DMSO (45 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Telaprevir | Hepatitis C protease inhibitor
    CAS:
    402957-28-2
    Catalog Number:
    10-4929
    Activity:
    HCV protease inhibitor
    Chemical Names:
    (3S,3aS,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
    Alternate Name:
    VX-950
    Molecular Weight:
    679.86
    Molecular Formula:
    C36H53N7O6
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Darunavir | HIV-1 protease inhibitor
    CAS:
    206361-99-1
    Catalog Number:
    10-4930
    Activity:
    HIV-1 protease inhibitor
    Chemical Names:
    [(3aS,4R,6aR)-2,3,3a,5,6a-Hexahydrofuro[2,3-b]furan-4-yl] N-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate; UIC-94017; TMC114
    Molecular Weight:
    547.67
    Molecular Formula:
    C27H37N3O7S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • GRL-0667 | Noncovalent inhibitor of SARS-CoV PLpro
    CAS:
    1234195-91-5
    Catalog Number:
    10-4963
    Activity:
    Noncovalent SARS-CoV Plpro inhibitor
    Chemical Names:
    1-[(R)-1-(1-Naphthyl)ethyl)]-4-[3,4-(methylenedioxy)benzylamino]carbonylpiperidine
    Molecular Weight:
    416.52
    Molecular Formula:
    C26H28N2O3
    Solubility:
    Soluble in DMSO (>25 mg/ml) or ethanol (15 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Viral proteases Products

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