GPCRs
Adenosine Adrenergic Calcium sensing Cannabinoid Chemokine Cholinergics Dopamine Estrogen Free fatty acid GABA Glutamate Histamine Hydroxycarboxylic acid Leukotriene Lysophosphatidic acid Melatonin Olfactory Orphan Opioid PAF Peptide Prostanoid Purinergic Serotonin Smoothened Sphingosine-1-phosphate TAAR Other GPCRs
Showing 1–12 of 114 results
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Adipogenesis
20(S)-Hydroxycholesterol | Smoothened activator
20(S)-Hydroxycholesterol (516-72-3) is an endogenous ligand for the LXR receptor.1 It has anti-adipogenic and pro-osteogenic effects in mesenchymal...$40.00 – $90.00 Select options -
Alzheimers
27-Hydroxycholesterol | Cholesterol oxidation metabolite
27-Hydroxycholesterol (20380-11-4) is a metabolite resulting from the action of sterol 27-hydroxylase on cholesterol. Concentrations of 27-hydroxyc...$40.00 – $175.00 Select options -
Dopamine
6,7-ADTN HBr | Dopamine D1 agonist
6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2 Demonstrates a marked selectivity for the human dopamine D3 receptor.3...$60.00 – $260.00 Select options -
Approved Drugs
9-Hydroxyrisperidone | Risperidone metabolite
9-Hydroxyrisperidone (144598-75-4) is a pharmacologically active metabolite of risperidone, an atypical antipsychotic agent.1 Displays high affinit...$30.00 – $110.00 Select options -
Alzheimers
ABT-418 HCl | Nicotinic acetylcholine receptor agonist/cognition enhancer
ABT-418 (CAS 147388-83-8) is an agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC5...$90.00 – $360.00 Select options -
New Products
AE 51310 | OPN4/melanopsin antagonist
AE 51310 (433966-92-8) is a potent antagonist of the GPCR OPN4/melanopsin (Ki = 0.096 nM human OPN4).1 OPN4 regulates circadian rhythms, pupil func...$50.00 – $195.00 Select options -
Bioactive Lipids
AH-6809 | Prostanoid EP antagonist
AH-6809 (33458-93-4) is a selective PGE2 receptor (EP1) antagonist. At concentrations higher than 10 μM PGD2 and TXA2 receptors are also blocked. ...$60.00 – $240.00 Select options -
Bioactive Lipids
AH-7614 | GPR120 antagonist
AH-7614 (6326-06-3) is a selective antagonist at free fatty acid receptor 4 (FFA4), also known as GPR120. pIC50s= 7.1 and 1. References/Citation...$45.00 – $180.00 Select options -
Approved Drugs
Allopregnanolone | GABA-A positive allosteric modulator
Allopregnanolone (516-54-1) is an endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approve...$70.00 – $280.00 Select options -
Cannabinoid
AM251 | Cannabinoid CB1 antagonist
AM251 (183232-66-8) is a potent cannabinoid CB1 receptor antagonist with selectivity over CB2 receptors (306-fold).1-3 Displays anorectic effects a...$72.00 – $290.00 Select options -
Bioactive Lipids
Anandamide | Endogenous cannabinoid
Anandamide (94421-68-8) is an endogenous cannabinoid receptor agonist.1-3 Ki=89 nM for CB1 and 371 nM for CB2 receptors. References/Citations: ...$35.00 – $135.00 Select options -
Approved Drugs
Apomorphine HCl | Dopamine agonist
Apomorphine (41372-20-7) is an archetypal dopamine pan-receptor agonist. Displays anti-Parkinsons activity in vivo.1 Protects against MPTP-induced ...$50.00 – $150.00 Select options
